[go: up one dir, main page]

Hirao et al., 1986 - Google Patents

Regioselective phenylcarbamoylation of purine and pyrimidine ribonucleosides through dibutyltin oxide-and tertiary amine-phenyl isocyanate systems

Hirao et al., 1986

Document ID
16562789753261079118
Author
Hirao I
Itoh K
Nishino S
Araki Y
Ishido Y
Publication year
Publication venue
Carbohydrate research

External Links

Snippet

Regioselective phenylcarbamoylation of ribonucleosides through the use of (Bu 2 SnO) n- PhNCO systems was revealed to have substantially the same tendency as observed in the reaction through (Bu 3 Sn) 2-O-PhNCO, giving the corresponding 3′-phenylcarbamates …
Continue reading at www.sciencedirect.com (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/09—Pyrimidine radicals with arabinosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C-Si linkages

Similar Documents

Publication Publication Date Title
US4082911A (en) Process for the preparation of nucleosides
Van Boom et al. The application of levulinic acid as protective group to the synthesis of tetradecaribonucleotide U‐A‐U‐A‐U‐A‐U‐A‐U‐A‐U‐A‐U‐A via the modified phosphotriester method
US4950745A (en) Process for synthesis of oligonucleotides and compound for forming polymeric protecting group
CA2057441C (en) Synthetic conversion of bryostatin 2 into bryostatin 1
EP0428109A2 (en) Deoxyfluoronucleoside process
Fukukawa et al. Synthesis of 2'-substituted derivatives of neplanocin A (nucleosides and nucleotides. XLIV)
Ferro et al. An improvement in the preparation of some carbohydrate benzylidene acetals
EP1261350B1 (en) Methods for synthesizing 2-chloro-9-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)-9h-purin-6-amine
Hirao et al. Regioselective phenylcarbamoylation of purine and pyrimidine ribonucleosides through dibutyltin oxide-and tertiary amine-phenyl isocyanate systems
US4691012A (en) Sialic acid derivative and process for preparing the same
US5011774A (en) Dideoxyinosine by enzymatic deamination of dideoxyadenosine
FR2500838A1 (en) DERIVATIVES OF NEPLANOCIN A
EP0339681A2 (en) Antitumor antibiotic substance
Chmielewski et al. [2+ 2] Cycloaddition of trichloroacetyl isocyanate to glycals
Hasegawa et al. An Unusual Behavior of Methyl or Benzyl 3-Azido-5-O-Benzoyl-3, 6-Di-Deoxy-α-L-Talofuranoside with (Dimethylamino) Sulfur Trifluoride; Migration of the Alkoxyl Group from the C-1 to the C-2 Position
Grøtli et al. Solid-phase synthesis of branched RNA and branched DNA/RNA chimeras
Fernandez-Fomer et al. Synthesis and characterization of oligodeoxynucleotides containing the mutagenic base analogue 4-O-ethylthymine
Hancox et al. Some reactions of 4′-thionucleosides and their sulfones
US4914028A (en) Method of preparing beta-2',2'-difluoronucleosides
GB2218417A (en) Preparation of diacyl derivatives of 2'-deoxy-5 fluorourdine via novel intermediate compound
US4656260A (en) Cyclic pyrazolo C-nucleoside compound and process for preparing the same
US4816575A (en) 2'-(R)-substituted-2'-deoxyneplanocin A derivatives
Hirao et al. Bis (tributyltin) oxide-phenyl isocyanate system for regioselective (phenylcarbamoyl) ation of purine and pyrimidine ribonucleosides
Smiatacz et al. The structure and properties of the products of reaction between 3, 4, 6-tri-O-acetyl-2-deoxy-2-nitroso-α-d-glucopyranosyl chloride and pyrazole
Marugg et al. (2‐Cyano‐1, 1‐dimethylethoxy) bis (diethylamino) phosphine: A convenient reagent for the synthesis of DNA fragments