Tang et al., 2019 - Google Patents
Activation of MT2 receptor ameliorates dendritic abnormalities in Alzheimer's disease via C/EBPα/miR‐125b pathwayTang et al., 2019
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- 1655547250610653940
- Author
- Tang H
- Ma M
- Wu Y
- Deng M
- Hu F
- Almansoub H
- Huang H
- Wang D
- Zhou L
- Wei N
- Man H
- Lu Y
- Liu D
- Zhu L
- Publication year
- Publication venue
- Aging Cell
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Snippet
Impairments of dendritic trees and spines have been found in many neurodegenerative diseases, including Alzheimer's disease (AD), in which the deficits of melatonin signal pathway were reported. Melatonin receptor 2 (MT2) is widely expressed in the hippocampus …
- 206010001897 Alzheimer's disease 0 title abstract description 45
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
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- C12N15/09—Recombinant DNA-technology
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- A—HUMAN NECESSITIES
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