Kairemo et al., 1999 - Google Patents
Ets-1 mRNA as target for antisense radio-oligonucleotide therapy in melanoma cellsKairemo et al., 1999
- Document ID
- 16220474683583062802
- Author
- Kairemo K
- Thorstensen K
- Mack M
- Tenhunen M
- Jekunen A
- Publication year
- Publication venue
- Gene Ther Mol Biol
External Links
- 101700033664 ETS1 0 title abstract description 38
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation; Therapies using these preparations
- A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Shi et al. | Downregulation of c-myc expression by antisense oligonucleotides inhibits proliferation of human smooth muscle cells. | |
| US5734039A (en) | Antisense oligonucleotides targeting cooperating oncogenes | |
| Lee et al. | O 6-Alkylguanine-DNA alkyltransferase depletion and regeneration in human peripheral lymphocytes following dacarbazine and fotemustine | |
| EP0458829B1 (en) | Methods and compositions for treatment of cancer using oligonucleotides | |
| US5618709A (en) | Antisense oligonucleotides specific for STK-1 and method for inhibiting expression of the STK-1 protein | |
| Kargiotis et al. | Effects of irradiation on tumor cell survival, invasion and angiogenesis | |
| Sgouros et al. | MIRD continuing education: bystander and low–dose-rate effects: are these relevant to radionuclide therapy? | |
| CN101951926A (en) | Radiation Sensitivity Enhanced Compositions Comprising MicroRNA-21 Inhibitors | |
| Varani et al. | In vitro and in vivo adherence of tumor cell variants correlated with tumor formation | |
| Kaplan et al. | The nucleus is the target for radiation-induced chromosomal instability | |
| AU5005093A (en) | Combination of antineoplastic agent and antisense oligonucleotides for treatment of cancer | |
| Kairemo et al. | Ets-1 mRNA as target for antisense radio-oligonucleotide therapy in melanoma cells | |
| US20040067197A1 (en) | Radiolabeled DNA carrier, method of preparation and therapeutic uses thereof | |
| Uckun et al. | Intrinsic radiation resistance of primary clonogenic blasts from children with newly diagnosed B-cell precursor acute lymphoblastic leukemia. | |
| US5821354A (en) | Radiolabeled DNA oligonucleotide and method of preparation | |
| Morgenroth et al. | Breaking the invulnerability of cancer stem cells: two-step strategy to kill the stem-like cell subpopulation of multiple myeloma | |
| Hill et al. | Lethal and kinetic effects of DDMP (2, 4-diamino-5-(3′, 4′-dichlorophenyl)-6-methylpyrimidine) | |
| Zvereva et al. | Oligonucleotide inhibitors of telomerase: prospects for anticancer therapy and diagnostics | |
| Glück et al. | Radiosensitivity of human clonogenic myeloma cells and normal bone marrow precursors: effect of different dose rates and fractionation | |
| US6339071B1 (en) | Antisense oligonucleotide modulating cyclin E gene expression and therapeutic uses thereof | |
| Abu-Gheida et al. | Radiobiology of stereotactic radiosurgery | |
| Masunaga et al. | Inhibition of repair of radiation-induced damage by mild temperature hyperthermia, referring to the effect on quiescent cell populations | |
| Lawrence et al. | Lack of dependence of 5-fluorodeoxyuridine-mediated radiosensitization on cytotoxicity | |
| KR101617749B1 (en) | Composition comprising HAS2 inhibitor for enhancing radiation sensitivity | |
| Harwood et al. | Utilization of 3H-5-uridine for RNA synthesis in ehrlich ascites tumour cells |