Wick, 2019 - Google Patents
Long-Range Inhibition in the Healthy and Epileptic HippocampusWick, 2019
View PDF- Document ID
- 16061645887871505747
- Author
- Wick Z
- Publication year
External Links
Snippet
There are many sources of inhibition and excitation that are carefully, and crucially, balanced within the brain. When this balance is off, pathological neuronal activity can emerge and lead to diseases such as epilepsy. My research identifies unique sources of …
- 210000001320 Hippocampus 0 title abstract description 175
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
- A01K67/027—New breeds of vertebrates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US9968652B2 (en) | Optically-controlled CNS dysfunction | |
| Kim et al. | Laminar restriction of retinal ganglion cell dendrites and axons: subtype-specific developmental patterns revealed with transgenic markers | |
| Brown et al. | The inhibitory microcircuit of the substantia nigra provides feedback gain control of the basal ganglia output | |
| Leroy et al. | Enkephalin release from VIP interneurons in the hippocampal CA2/3a region mediates heterosynaptic plasticity and social memory | |
| Yin et al. | A central amygdala–ventrolateral periaqueductal gray matter pathway for pain in a mouse model of depression-like behavior | |
| Lalive et al. | Motor thalamus supports striatum-driven reinforcement | |
| Aquino-Miranda et al. | Functional properties of corticothalamic circuits targeting paraventricular thalamic neurons | |
| Wong et al. | Artificial fluorescent sensor reveals pre‐synaptic NMDA receptors switch cholecystokinin release and LTP in the hippocampus | |
| Shen et al. | Astrocytic GAT‐3 Regulates Synaptic Transmission and Memory Formation in the Dentate Gyrus | |
| Dilger et al. | Requirements for synaptically evoked plateau potentials in relay cells of the dorsal lateral geniculate nucleus of the mouse | |
| Wick | Long-Range Inhibition in the Healthy and Epileptic Hippocampus | |
| Christenson Wick | Long-range inhibition in the healthy and epileptic hippocampus | |
| Gowrishankar et al. | Endogenous opioid dynamics in the dorsal striatum sculpt neural activity to control goal-directed action | |
| Malgady et al. | Non-synaptic alterations in striatal excitability and cholinergic modulation in a SAPAP3 mouse model of compulsive motor behavior | |
| Christenson Wick et al. | A novel population of long-range inhibitory neurons | |
| Doolittle | The Influence of Autism Linked Gene Topoisomerase 3B (Top3B) on Neural Development in Zebrafish | |
| Pepin | A cortico-amygdala circuit controls the striatal memory system supporting the effect of predictive learning on choice between actions | |
| Lee et al. | Distinct modes of dopamine modulation on striatopallidal synaptic transmission | |
| Li | How does the neural circuitry of the hippocampal dentate gyrus shape our memories? | |
| Rosés-Novella | The role of Shank3 in the wiring of VIP interneurons in the mouse visual cortex | |
| Mays | An Experimental Toolkit for Analysis of Single Monoaminergic Axons in the Mouse Brain | |
| Gulfo | Cellular Mechanisms of Neuromodulation in the Dentate Gyrus | |
| George | Contributions of myelinated axonal adaptations to olfactory sensory processing | |
| Traba | Dopamine receptor modulation of motivation and reinforcement in the nucleus accumbens | |
| Frezel | Modulation of sensory processing by direct descending projections from the somatosensory cortex to the spinal dorsal horn |