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Tanji et al., 2015 - Google Patents

DPP-4 inhibition ameliorates pancreatic β-cell failure and improves glucose tolerance in the mouse model of Wolfram syndrome

Tanji et al., 2015

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Document ID
15190102167563784514
Author
Tanji Y
Yamaguchi S
Ishigaki Y
Katagiri H
Oka Y
Ishihara H
Publication year
Publication venue
Journal of Diabetes Mellitus

External Links

Snippet

Wolfram syndrome, an autosomal recessive disorder associated with diabetes and optic atrophy, is caused by mutations in the WFS1 gene encoding wolframin, an endoplasmic reticulum membrane protein. Recent development of incretin-based drugs demonstrates …
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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