HAMADA et al., 1985 - Google Patents
Identification of a thyroid microsomal antigen by Western blot and immunoprecipitationHAMADA et al., 1985
- Document ID
- 15042653919750684205
- Author
- HAMADA N
- GRIMM C
- MORI H
- DEGROOT L
- Publication year
- Publication venue
- The Journal of Clinical Endocrinology & Metabolism
External Links
Snippet
The molecular identity of the thyroid microsomal antigen was investigated by Western blot and immunoprecipitation using sera from eight patients with autoimmune thyroid disease. All sera had high microsomal antibody titers by hemagglutination test and ELISA; only one had …
- 230000003228 microsomal 0 title abstract description 61
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/564—Immunoassay; Biospecific binding assay for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses, e.g. hepatitis E virus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/10—Musculoskeletal or connective tissue disorders
- G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HAMADA et al. | Identification of a thyroid microsomal antigen by Western blot and immunoprecipitation | |
CA1222449A (en) | Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays | |
Guilbert et al. | Naturally occurring antibodies against nine common antigens in human sera. I. Detection, isolation and characterization. | |
Eriksson et al. | Cellular retinol-binding protein. Quantitation and distribution. | |
Edgington et al. | The assessment by immunofluorescence methods of humoral anti-myelin antibodies in man | |
JP2780020B2 (en) | Human T cell leukemia virus antigen and detection method using the antigen | |
Berneman et al. | IgG auto-and polyreactivities of normal human sera | |
Yoshioka et al. | Detection of hidden nephritogenic antigen determinants in human renal and nonrenal basement membranes | |
Doble et al. | Autoantibodies to the thyroid microsomal/thyroid peroxidase antigen are polyclonal and directed to several distinct antigenic sites | |
Mappouras et al. | Antibodies to acetylcholinesterase cross-reacting with thyroglobulin in myasthenia gravis and Graves' disease | |
Baker Jr et al. | An analysis of the structure and antigenicity of different forms of human thyroid peroxidase | |
Imai et al. | Immunologic characterization and molecular profile of carcinoembryonic antigen detected by monoclonal antibodies. | |
HAMADA et al. | Antibodies against denatured and reduced thyroid microsomal antigen in autoimmune thyroid disease | |
Harmon et al. | Identification of human leukemic glucocorticoid receptors using affinity labeling and anti-human glucocorticoid receptor antibodies | |
Butler et al. | A reliable method for the preparation of bovine secretory immunoglobulin A (SIgA) which circumvents problems posed by IgG1 dimers in colostrum | |
JP2001505999A (en) | Receptor binding assay for detecting TSH receptor autoantibodies | |
van der Schoot et al. | Characterization of platelet‐specific alloantigens by immimoblotting: localization of Zw and Bak antigens | |
Banga et al. | Thyroid microsomal/thyroid peroxidase autoantibodies show discrete patterns of cross-reactivity to myeloperoxidase, lactoperoxidase and horseradish peroxidase | |
Shy et al. | Specificity of human IgM M-proteins that bind to myelin-associated glycoprotein: peptide mapping, deglycosylation, and competitive binding studies. | |
Heyma et al. | Precipitation of the thyrotropin receptor and identification of thyroid autoantigens using Graves' disease immunoglobulins. | |
Kaplan et al. | Platelet antibodies in systemic lupus erythematosus | |
Monteiro et al. | Serum IgA preferentially binds to cationic polypeptides in IgA nephropathy | |
Mariotti et al. | A new solid phase immunoradiometric assay for antithyroid microsomal antibody | |
US5175148A (en) | Sperm antigen corresponding to a sperm autoantigenic epitope and methods of using the same | |
Sloan et al. | Identification of phosphorylcholine containing antigens of Fasciola hepatica—successful tolerization against this epitope in experimental animals |