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Nath et al., 2013 - Google Patents

A Review on Novel Formulation Approaches of Azidothymidine

Nath et al., 2013

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Document ID
15010059403738760218
Author
Nath J
Hari B
Devi D
Publication year
Publication venue
Journal of Pharmaceutical Sciences and Research

External Links

Snippet

Azidothymidine (AZT or ZVD), a Nucleoside Reverse Transcriptase Inhibitor (NRTI), is used as antiviral medication to treat Human Immunodeficiency Virus (HIV) which causes Acquired Immunodeficiency Syndrome (AIDS). It is the first approved anti HIV drug for AIDS used …
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Classifications

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    • A61K9/16—Agglomerates; Granulates; Microbeadlets; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
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