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Koscielny et al., 2007 - Google Patents

Ximelagatran for treatment and prophylaxis of recurrent events in deep vein thrombosis

Koscielny et al., 2007

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Document ID
14760930831638997447
Author
Koscielny J
Kiesewetter H
Jörg I
Harenberg J
Publication year
Publication venue
Clinical and Applied Thrombosis/Hemostasis

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Snippet

The treatment of acute venous thromboembolism and prophylaxis of recurrent events with heparin/low molecular weight heparin followed by vitamin K antagonists is limited by several factors. Oral direct thrombin inhibitors (ODTIs) showed a better pharmacological activity and …
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
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