Romagnoli et al., 1990 - Google Patents
Peptide-MHC interaction: a rational approach to vaccine designRomagnoli et al., 1990
- Document ID
- 14745239759250985214
- Author
- Romagnoli P
- Takacs B
- Kilgus J
- Pink J
- Sinigaglia F
- Publication year
- Publication venue
- International reviews of immunology
External Links
Snippet
The goal of vaccination is to induce a protective immune response without inducing the disease itself or other undesirable effects. In the past this was achieved by giving inactivated or attenuated pathogens, with notable success in some cases, but problems of safety …
- 229960005486 vaccines 0 title abstract description 20
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US5114713A (en) | P. falciparum cs-peptides as universal t-cell epitope | |
Etlinger et al. | Assessment in humans of a synthetic peptide-based vaccine against the sporozoite stage of the human malaria parasite, Plasmodium falciparum. | |
Calvo-Calle et al. | Binding of malaria T cell epitopes to DR and DQ molecules in vitro correlates with immunogenicity in vivo: identification of a universal T cell epitope in the Plasmodium falciparum circumsporozoite protein | |
Hashim et al. | Antibodies specific for VB8 receptor peptide suppress experimental autoimmune encephalomyelitis. | |
Del Guercio et al. | Potent immunogenic short linear peptide constructs composed of B cell epitopes and Pan DR T helper epitopes (PADRE) for antibody responses in vivo | |
JP2573815B2 (en) | Mycobacterium infection detection synthetic polypeptide | |
US6410022B1 (en) | Modulation of cholesteryl ester transfer protein (CETP) activity | |
CA2027317A1 (en) | Vaccine composition with non-immunosuppressive t-cell epitope component | |
US5019384A (en) | Immunonodulating compositions and their use | |
US5231168A (en) | Malaria antigen | |
Beachey et al. | Epitope-specific protective immunogenicity of chemically synthesized 13-, 18-, and 23-residue peptide fragments of streptococcal M protein. | |
Partidos et al. | The effect of orientation of epitopes on the immunogenicity of chimeric synthetic peptides representing measles virus protein sequences | |
NO167359B (en) | PROCEDURE FOR THE PREPARATION OF A VACCINE AGAINST INFECTION OF HEPATITIS B VIRUS. | |
CA2129747C (en) | Peptide for diagnosing and immunizing against t. cruzi infection | |
IE56627B1 (en) | Protective peptide antigen | |
Fitzmaurice et al. | The assembly and immunological properties of non-linear synthetic immunogens containing T-cell and B-cell determinants | |
WO1986005790A1 (en) | Immunogenic antigen-carrier protein conjugate for use in a vaccine against malaria | |
Romagnoli et al. | Peptide-MHC interaction: a rational approach to vaccine design | |
Arnon | Peptides as immunogens: prospects for synthetic vaccines | |
CA2041271A1 (en) | Peptide analogs to proteins of the immunoglobin superfamily | |
Dyrberg et al. | Immunological cross-reactivity between mimicking epitopes on a virus protein and a human autoantigen depends on a single amino acid residue | |
Sinigaglia et al. | Malaria antigens and MHC restriction | |
Dadley-Moore et al. | Synthetic peptide antigens induce antibodies to Taenia ovis oncospheres | |
Kakimoto et al. | Specificity of anti-type II collagen antibody response in rats | |
Mishra et al. | Human T-helper cell responses to a synthetic peptide derived from the hepatitis B surface antigen |