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Singer et al., 2003 - Google Patents

Poly-(L)-glutamic acid-paclitaxel (CT-2103)[XYOTAX™], a biodegradable polymeric drug conjugate: Characterization, preclinical pharmacology, and preliminary …

Singer et al., 2003

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Document ID
1472633392702497563
Author
Singer J
Baker B
De Vries P
Kumar A
Shaffer S
Vawter E
Bolton M
Garzone P
Publication year
Publication venue
Polymer drugs in the clinical stage: advantages and prospects

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Conclusions These data describing the preclinical and early clinical development of CT- 2103 demonstrate the feasibility of using polyglutamic acid homopolymers to create macromolecular cytotoxic drug conjugates. PG has the characteristics of an ideal polymeric …
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