Brynes et al., 1978 - Google Patents
Potential antitumor agents via inhibitors of L‐asparagine synthetase: Substituted sulfonamides and sulfonyl hydrazides related to glutamineBrynes et al., 1978
- Document ID
- 14282600952527838332
- Author
- Brynes S
- Fiorina V
- Cooney D
- Milman H
- Publication year
- Publication venue
- Journal of Pharmaceutical Sciences
External Links
Snippet
A series of 4‐(substituted aminosulfonyl)‐and 4‐(substituted hydrazinosulfonyl)‐2‐ aminobutanoic acids, compounds structurally related to glutamine, was synthesized as potential inhibitors of L‐asparagine synthetase and subjected to screening as antitumor …
- 229960001230 Asparagine 0 title abstract description 15
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
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