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Macomber et al., 1985 - Google Patents

A Horner‐Emmons Approach to Cumulatrienes

Macomber et al., 1985

Document ID
13936287526738571573
Author
Macomber R
Hemling T
Publication year
Publication venue
Israel Journal of Chemistry

External Links

Snippet

Reaction of allenic phosphonates of structure (R'O) 2P (O) CH′ C CR2 with LDA led to ylid‐like carbanions (2) by removal of H′. Intermediate 2 reacted with a variety of ketones (R′ 2′ C O) to give adducts (3) which fragmented to cumulatrienes of structure R …
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P-C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4056—Esters of arylalkanephosphonic acids
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
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