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González-Gómez et al., 2002 - Google Patents

A cyclative cleavage approach to the solid phase synthesis of 2-oxo-1, 4-piperazines

González-Gómez et al., 2002

Document ID
13650650781804989582
Author
González-Gómez J
Uriarte-Villares E
Figueroa-Pérez S
Publication year
Publication venue
Synlett

External Links

Snippet

A new facile solid phase synthesis of 2-oxo-1, 4-piperazines is described. α-N-Boc-amino aldehydes, which were generated in situ by oxidation of commercially available α-amino alcohols promoted by a polymer supported bromite, were used for the reductive amination of …
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL CHEMISTRY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL CHEMISTRY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—For creating libraries
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL CHEMISTRY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/18—Libraries containing only inorganic compounds or inorganic materials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL CHEMISTRY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
    • C40B30/00—Methods of screening libraries

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