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Doran et al., 2004 - Google Patents

Production of siRNAs with the Application of Deoxyribozymes

Doran et al., 2004

Document ID
13617928544483625199
Author
Doran G
Sohail M
Publication year
Publication venue
Gene Silencing by RNA Interference

External Links

Snippet

Exogenous application of siRNAs is becoming a widely used approach to achieve gene knockdown. 1 However, siRNAs targeted to different regions of a gene exhibit different efficacies, 2-4 and often several reagents may have to be screened for optimal activity …
Continue reading at www.taylorfrancis.com (other versions)

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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/6832—Enhancement of hybridisation reaction
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/101—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by chromatography, e.g. electrophoresis, ion-exchange, reverse phase
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
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