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García-Rodríguez et al., 2024 - Google Patents

Similar mechanisms of retron-mediated anti-phage defense for different families of tailed phages

García-Rodríguez et al., 2024

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Document ID
1333290912534784458
Author
García-Rodríguez F
Martínez-Abarca F
Wilkinson M
Toro N
Publication year
Publication venue
bioRxiv

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Snippet

Bacterial retrons are tripartite systems consisting of a cognate non-coding RNA, reverse transcriptase, and additional (effector) protein with diverse predicted enzymatic functions. In this study, we investigated the role and mechanism of Retron-Eco11, a novel type III-A3 …
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
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    • C12N2795/00—Bacteriophages
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