[go: up one dir, main page]

Hosseini et al., 2019 - Google Patents

Contribution of osteocalcin-mimetic peptide enhances osteogenic activity and extracellular matrix mineralization of human osteoblast-like cells

Hosseini et al., 2019

View PDF
Document ID
13041627484175003298
Author
Hosseini S
Naderi-Manesh H
Vali H
Eslaminejad M
Sayahpour F
Sheibani S
Faghihi S
Publication year
Publication venue
Colloids and Surfaces B: Biointerfaces

External Links

Snippet

A natural peptide motif in the first helix of osteocalcin (OCN) is used to promote nucleation and crystallization of hydroxyapatite (HA) in hard tissue. The capability of osteocalcin mimetic peptides to induce osteogenic activity of osteoblast cells leading to in-vitro …
Continue reading at www.academia.edu (PDF) (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances

Similar Documents

Publication Publication Date Title
Hosseini et al. Contribution of osteocalcin-mimetic peptide enhances osteogenic activity and extracellular matrix mineralization of human osteoblast-like cells
Maegawa et al. Enhancement of osteoblastic differentiation of mesenchymal stromal cells cultured by selective combination of bone morphogenetic protein‐2 (BMP‐2) and fibroblast growth factor‐2 (FGF‐2)
Yu et al. Bone morphogenetic protein 2 stimulates endochondral ossification by regulating periosteal cell fate during bone repair
Chiu et al. The effect of type II collagen on MSC osteogenic differentiation and bone defect repair
Sila-Asna et al. Osteoblast differentiation and bone formation gene expression in strontium-inducing bone marrow mesenchymal stem cell
CA2681317C (en) A synthetic peptide containing bone forming peptide 1(bfp 1) for stimulating osteoblast differentiation, and pharmaceutical composition comprising the synthetic peptide
Hang et al. Apelin enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly through Wnt/β-catenin signaling pathway
González et al. Treatment of a murine model of high-turnover renal osteodystrophy by exogenous BMP-7
Guo et al. Mechanical strain promotes osteoblast ECM formation and improves its osteoinductive potential
Kawazoe et al. Activation of the FGF signaling pathway and subsequent induction of mesenchymal stem cell differentiation by inorganic polyphosphate
Felthaus et al. Dexamethasone-related osteogenic differentiation of dental follicle cells depends on ZBTB16 but not Runx2
EP2303911B1 (en) A synthetic peptide consisting of bone forming peptide 2(bfp 2) for stimulating osteoblast differentiation, and pharmaceutical composition comprising the synthetic peptide
Ravikumar et al. Synergy of substrate conductivity and intermittent electrical stimulation towards osteogenic differentiation of human mesenchymal stem cells
Li et al. Biphasic effects of TGFβ1 on BMP9-induced osteogenic differentiation of mesenchymal stem cells
Huo et al. Chrysin induces osteogenic differentiation of human dental pulp stem cells
Schwartz et al. Osteoprotegerin (OPG) production by cells in the osteoblast lineage is regulated by pulsed electromagnetic fields in cultures grown on calcium phosphate substrates
Liu et al. Effect of NELL1 gene overexpression in iPSC-MSCs seeded on calcium phosphate cement
Pizzicannella et al. Bovine pericardium membrane, gingival stem cells, and ascorbic acid: a novel team in regenerative medicine
Zhi et al. Synergistic effect of recombinant human bone morphogenic protein-7 and osteogenic differentiation medium on human bone-marrow-derived mesenchymal stem cells in vitro
Lee et al. Combined effects of dentin sialoprotein and bone morphogenetic protein-2 on differentiation in human cementoblasts
Ono et al. Promotion of attachment of human bone marrow stromal cells by CCN2
US8025872B2 (en) Osteogenic synthetic peptides, pharmaceutical compositions comprising the same, and medium containing the same
Tsai et al. Type I collagen structure modulates the behavior of osteoblast-like cells
Wang et al. Cytoskeleton reorganization and FAK phosphorylation are involved in lanthanum (III)-promoted proliferation and differentiation in rat osteoblasts
JP5819298B2 (en) Use of type VII collagen for maintaining and reinducing osteogenic capacity of mesenchymal stem cells