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Asthana et al., 1995 - Google Patents

Treatment of Alzheimer disease by continuous intravenous infusion of physostigmine

Asthana et al., 1995

Document ID
1298640075325463514
Author
Asthana S
Raffaele K
Berardi A
Greig N
Haxby J
Schapiro M
Soncrant T
Publication year
Publication venue
Alzheimer Disease & Associated Disorders

External Links

Snippet

Physostigmine, a reversible and nonselective cholinesterase inhibitor, administered by steady-state, continuous intravenous infusion to carefully selected subjects with mild- moderate Alzheimer disease, produced significant but modest improvement in memory in …
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Classifications

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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