[go: up one dir, main page]

Marcus et al., 1971 - Google Patents

Interferon action: inhibition of vesicular stomatitis virus RNA synthesis induced by virion-bound polymerase

Marcus et al., 1971

Document ID
12912158310302515
Author
Marcus P
Engelhardt D
Hunt J
Sekellick M
Publication year
Publication venue
Science

External Links

Snippet

The particle-bound RNA polymerase activity of vesicular stomatitis virus (VSV) can be demonstrated in vivo. Linear synthesis of viral RNA persists for 5 to 6 hours at 34° C in infected monolayers of chick embryo cells treated with cycloheximide and actinomycin D to …
Continue reading at www.science.org (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation; Therapies using these preparations

Similar Documents

Publication Publication Date Title
Marcus et al. Interferon action: inhibition of vesicular stomatitis virus RNA synthesis induced by virion-bound polymerase
JP4267693B2 (en) Method for enhancing virus vaccine production in cell culture by interferon suppression
Alexander et al. Analysis of the role of autophagy in replication of herpes simplex virus in cell culture
Fleischmann Jr et al. Potentiation of interferon activity by mixed preparations of fibroblast and immune interferon
Di Luca et al. The replication of viral and cellular DNA in human herpesvirus 6-infected cells
Clavell et al. Relationship between the ribonucleic acid-synthesizing capacity of ultraviolet-irradiated Newcastle disease virus and its ability to induce interferon
Krishnan et al. 2′ 5′ oligo (A) polymerase activity in serum of mice infected with EMC virus or treated with interferon
TS’O et al. An integrated and comparative study of the antiviral effects and other biological properties of the polyinosinic acid-polycytidylic acid and its mismatched analogues
McAuslan et al. Deoxyribonucleic acid synthesis in FV-3-infected mammalian cells
Kaplan et al. Isolation of simian virus 40-transformed inbred hamster cell lines heterogeneous for virus induction by chemicals or radiation
Vigne et al. Restitution of fibroblast-transforming ability in srcdeletion mutants of avian sarcoma virus during animal passage
JPH02502424A (en) Methods for the preparation of antigen-specific T cell lines and their use for therapy
Pisciotta et al. Studies on agranulocytosis. Al. Limited proliferative potential of GK-sensitive patients
CN119101665A (en) A recombinant oncolytic virus VSV-sPD1IL15RaIL15 and its construction method and application
Eckner Continuous replication of Friend virus complex (spleen focus-forming virus-lymphatic leukemia-inducing virus) in mouse embryo fibroblasts. Retention of leukemogenicity and loss of immunosuppressive properties.
Miller The nucleic acid content of influenza virus
Kucera et al. Herpes simplex virus type 2 functions expressed during stimulation of human cell DNA synthesis
Brailovsky et al. Decreased interferon sensitivity and production in cells transformed by SV40 and other oncogenic agents
Barmak et al. Altered cellular responses to interferon induction by poly I· poly C: Priming and hyporesponsiveness in cells treated with interferon preparations
Schrom et al. Altered cellular morphology resulting from cytocidal virus infection
Henderson et al. Effects of nucleoside analogs on Epstein-Barr virus-induced transformation of human umbilical cord leukocytes and Epstein-Barr virus expression in transformed cells
Naruse et al. Temperature-sensitive mutants of fowl plague virus defective in the intracellular transport of the hemagglutinin
Cox et al. Comparative studies of wild-type and cold-mutant (temperature-sensitive) influenza virus: detection of mutations in all genes of the A/Ann Arbor/6/60 (H2N2) mutant vaccine donor strain
Bhat et al. The complexity of mitochondrial translation products in mammalian cells
Hashimoto et al. The Mode of Production of Endotoxin‐Induced Interferon in Rabbit Tissue Cells: I. Development of Priming by Pretreatment with Interferon