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Wu et al., 2021 - Google Patents

Conditional gene silencing via a CRISPR system in cerebellar Purkinje cells

Wu et al., 2021

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Document ID
12870297386604637197
Author
Wu Q
Kapfhammer J
Publication year
Publication venue
Biochimica et Biophysica Acta (BBA)-General Subjects

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Snippet

Specific gene knockdown in cerebellar Purkinje cells is a major challenge because Purkinje cells only make up a small fraction of the cerebellum and off-target effects of shRNA occur.• Little is known about the application of CRISPR-Cas13 and the resulting protein expression …
Continue reading at www.sciencedirect.com (HTML) (other versions)

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