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Aparici et al., 2019 - Google Patents

Pharmacological profile of AZD8871 (LAS191351), a novel inhaled dual M3 receptor antagonist/β2-adrenoceptor agonist molecule with long-lasting effects and …

Aparici et al., 2019

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Document ID
1270200705104736197
Author
Aparici M
Carcasona C
Ramos I
Montero J
Otal R
Ortiz J
Cortijo J
Puig C
Vilella D
De Alba J
Doe C
Gavaldà A
Miralpeix M
Publication year
Publication venue
The Journal of Pharmacology and Experimental Therapeutics

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AZD8871 is a novel muscarinic antagonist and β 2-adrenoceptor agonist in development for chronic obstructive pulmonary disease. This study describes the pharmacological profile of AZD8871 in in vitro and in vivo assays. AZD8871 is potent at the human M 3 receptor (pIC …
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