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Lambeth et al., 2012 - Google Patents

Short hairpin RNA-mediated gene silencing

Lambeth et al., 2012

Document ID
12680355761814509048
Author
Lambeth L
Smith C
Publication year
Publication venue
siRNA design: methods and protocols

External Links

Snippet

Since the first application of RNA interference (RNAi) in mammalian cells, the expression of short hairpin RNAs (shRNAs) for targeted gene silencing has become a benchmark technology. Using plasmid and viral vectoring systems, the transcription of shRNA …
Continue reading at link.springer.com (other versions)

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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C12N2310/141—MicroRNAs, miRNAs
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