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Ziebuhr et al., 2007 - Google Patents

Human coronavirus 229E papain-like proteases have overlapping specificities but distinct functions in viral replication

Ziebuhr et al., 2007

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Document ID
1250089265580277127
Author
Ziebuhr J
Schelle B
Karl N
Minskaia E
Bayer S
Siddell S
Gorbalenya A
Thiel V
Publication year
Publication venue
Journal of virology

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Snippet

Expression of the exceptionally large RNA genomes of CoVs involves multiple regulatory mechanisms, including extensive proteolytic processing of the large replicase polyproteins, pp1a and pp1ab, by two types of cysteine proteases: the chymotrypsin-like main protease …
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    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases Endopeptidases (3.4.21-3.4.25)
    • C12N9/503—Proteinases Endopeptidases (3.4.21-3.4.25) derived from viruses
    • C12N9/506—Proteinases Endopeptidases (3.4.21-3.4.25) derived from viruses derived from RNA viruses
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