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Juma et al., 2009 - Google Patents

Synthesis of 2, 6‐Dioxo‐1, 2, 3, 4, 5, 6‐hexahydroindoles by Acid‐Catalyzed Cyclization of Acetal‐Protected (2, 4‐Dioxocyclohex‐1‐yl) acetamides and their …

Juma et al., 2009

Document ID
1249730667201019162
Author
Juma B
Adeel M
Villinger A
Reinke H
Spannenberg A
Fischer C
Langer P
Publication year
Publication venue
Advanced Synthesis & Catalysis

External Links

Snippet

Abstract Acetal‐protected (2, 4‐dioxocyclohex‐1‐yl) acetic acids were prepared by allylation of dilithiated 1, 3‐cyclohexane‐1, 3‐diones, protection of the carbonyl groups and oxidation of the alkene moiety. Their reaction with amines afforded the corresponding amides which …
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    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
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    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C07C45/676—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton by elimination of carboxyl groups
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