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Jamaluddin et al., 2007 - Google Patents

Conformational changes Induced by Binding UDP-2F-galactose to α-1, 3 Galactosyltransferase-implications for catalysis

Jamaluddin et al., 2007

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Document ID
12461252857704925391
Author
Jamaluddin H
Tumbale P
Withers S
Acharya K
Brew K
Publication year
Publication venue
Journal of molecular biology

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Snippet

α-1, 3 Galactosyltransferase (α3GT) catalyzes the transfer of galactose from UDP-galactose to β-linked galactosides with retention of its α configuration. Although several complexes of α3GT with inhibitors and substrates have been reported, no structure has been determined …
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
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    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
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    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
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