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Khanna et al., 1999 - Google Patents

Multiplex PCR/LDR for detection of K-ras mutations in primary colon tumors

Khanna et al., 1999

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Document ID
1229411023718828547
Author
Khanna M
Park P
Zirvi M
Cao W
Picon A
Day J
Paty P
Barany F
Publication year
Publication venue
Oncogene

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Abstract Point mutations in codons 12, 13, and 61 of the K-ras gene occur early in the development of colorectal cancer and are preserved throughout the course of tumor progression. These mutations can serve as biomarkers for shed or circulating tumor cells …
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