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Natesan et al., 2017 - Google Patents

Chitosan stabilized camptothecin nanoemulsions: Development, evaluation and biodistribution in preclinical breast cancer animal mode

Natesan et al., 2017

Document ID
1209384860154387238
Author
Natesan S
Sugumaran A
Ponnusamy C
Thiagarajan V
Palanichamy R
Kandasamy R
Publication year
Publication venue
International journal of biological macromolecules

External Links

Snippet

Clinical use of camptothecin (CPT) is hindered due to its poor water and oil solubility, active lactone ring instability and non-targeted toxicity. Recently we reported formulation of camptothecin microemulsions with increased solubility for the improved treatment of breast …
Continue reading at www.sciencedirect.com (other versions)

Classifications

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    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
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    • A61K9/513—Organic macromolecular compounds; Dendrimers
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    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
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