Newling et al., 2018 - Google Patents
Fc gamma receptor IIa suppresses type I and III interferon production by human myeloid immune cellsNewling et al., 2018
View PDF- Document ID
- 11938780294684134914
- Author
- Newling M
- Hoepel W
- Vogelpoel L
- Heineke M
- van Burgsteden J
- Taanman‐Kueter E
- Eggink D
- Kuijpers T
- Beaumont T
- van Egmond M
- Kapsenberg M
- Baeten D
- den Dunnen J
- Jong E
- Publication year
- Publication venue
- European Journal of Immunology
External Links
Snippet
Type I and type III interferons (IFNs) are fundamental for antiviral immunity, but prolonged expression is also detrimental to the host. Therefore, upon viral infection high levels of type I and III IFNs are followed by a strong and rapid decline. However, the mechanisms …
- 108010021468 Fc gamma receptor IIA 0 title abstract description 56
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Leylek et al. | Integrated cross-species analysis identifies a conserved transitional dendritic cell population | |
| Schaupp et al. | Microbiota-induced type I interferons instruct a poised basal state of dendritic cells | |
| Newling et al. | Fc gamma receptor IIa suppresses type I and III interferon production by human myeloid immune cells | |
| Crow et al. | Type I interferons in autoimmune disease | |
| Accapezzato et al. | Advances in the pathogenesis and treatment of systemic lupus erythematosus | |
| Yu et al. | Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age | |
| Szappanos et al. | The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity | |
| Bencze et al. | Type I interferon production of plasmacytoid dendritic cells under control | |
| Backer et al. | A central role for Notch in effector CD8+ T cell differentiation | |
| Ma et al. | Functional STAT3 deficiency compromises the generation of human T follicular helper cells | |
| Channappanavar et al. | Dysregulated type I interferon and inflammatory monocyte-macrophage responses cause lethal pneumonia in SARS-CoV-infected mice | |
| Wang et al. | The autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunity | |
| Vella et al. | CD4+ T cell differentiation in chronic viral infections: the Tfh perspective | |
| Nagasaka et al. | Osteopontin is produced by mast cells and affects IgE‐mediated degranulation and migration of mast cells | |
| Ju et al. | Modulation of STAT‐3 in rheumatoid synovial T cells suppresses Th17 differentiation and increases the proportion of Treg cells | |
| Coquery et al. | BAFF regulates follicular helper T cells and affects their accumulation and interferon‐γ production in autoimmunity | |
| Kvarnhammar et al. | NOD‐like receptors and RIG‐I‐like receptors in human eosinophils: activation by NOD1 and NOD2 agonists | |
| Staels et al. | Monogenic adult-onset inborn errors of immunity | |
| Phipps-Yonas et al. | Interferon-β pretreatment of conventional and plasmacytoid human dendritic cells enhances their activation by influenza virus | |
| Heger et al. | XCR1 expression distinguishes human conventional dendritic cell type 1 with full effector functions from their immediate precursors | |
| Simpson et al. | T Cells Produce IFN-α in the TREX1 D18N Model of Lupus-like Autoimmunity | |
| Barut et al. | Transcriptomic profiling of bovine blood dendritic cells and monocytes following TLR stimulation | |
| Mancuso et al. | Effects of B-cell lymphoma on the immune system and immune recovery after treatment: the paradigm of targeted therapy | |
| Thelen et al. | Eomes is sufficient to regulate IL-10 expression and cytotoxic effector molecules in murine CD4+ T cells | |
| Rashu et al. | Targeting the MR1-MAIT cell axis improves vaccine efficacy and affords protection against viral pathogens |