[go: up one dir, main page]

Sauer et al., 1969 - Google Patents

Biosynthesis of pregnane derivatives in Strophanthus kombe

Sauer et al., 1969

Document ID
11853021390723947895
Author
Sauer H
Bennett R
Heftmann E
Publication year
Publication venue
Phytochemistry

External Links

Snippet

The following radioactive pregnane derivatives were isolated from Strophanthus kombé plants after administration of progesterone-4-14 C: 5α-pregnane-3, 20-dione, 5α-pregnan- 3β-ol-20-one, 5β-pregnane-3, 20-dione, 5β-pregnan-3β-ol-20-one, 5β-pregnane-3β, 20β …
Continue reading at www.sciencedirect.com (other versions)

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036Nitrogen-containing hetero ring
    • C07J71/0042Nitrogen only
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J53/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002Carbocyclic rings fused
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0059Estrane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J63/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008Expansion of ring D by one atom, e.g. D homo steroids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0066Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005Ketals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0018Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J13/00Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Similar Documents

Publication Publication Date Title
Fukushima et al. The characterization of four new metabolites of adrenocortical hormones
Willett et al. Squalene-2, 3-oxide, an intermediate in the enzymatic conversion of squalene to lanosterol and cholesterol
Dehennin et al. Simple methods for the synthesis of twenty different, highly enriched deuterium labelled steroids, suitable as internal standards for isotope dilution mass spectrometry
Bennett et al. Biosynthesis of Dioscorea sapogenins from cholesterol
Schänzer et al. Metabolism of anabolic steroids in humans: Synthesis of 6β-hydroxy metabolites of 4-chloro-1, 2-dehydro-17α-methyltestosterone, fluoxymesterone, and metandienone
JPS6333395A (en) Novel 3,20-dioxo-4,9-diene-21-hydroxylsteroid derivative
Sauer et al. Biosynthesis of pregnane derivatives in Strophanthus kombe
Kvasnica et al. Synthesis, characterization and antiproliferative activity of seco analogues of brassinosteroids
Knight et al. The Structure of the cactus sterol macdougallin (14α-Methyl-Δ8-cholestene-3β, 6α-diol). A novel link in sterol biogenesis1, 2
Kelly et al. Isolation and characterization of human urinary metabolites of aldosterone. IV. The synthesis and stereochemistry of two bicyclic acetal metabolites
Barber et al. INVESTIGATIONS ON STEROIDS. XXV. 19-OXOPROGESTERONE AND 19-OXO-11-DESOXYCORTICOSTERONE*, 1
EHRENSTEIN et al. INVESTIGATIONS ON STEROIDS. III. PARTIAL OXIDATION OF 3, 5, 6-TRIOLS AND OXIDATION WITH PERMANGANATE OF 5, 6-UNSATURATED STEROIDS1
ISHIGURO et al. Stereochemistry of Electrophilic Reactions at the Steroidal C-22 Double Bond
Mallory et al. The Grignard addition to steroidal cyclic ketals
KASAI et al. Constituents of Chinese Crude Drug" Wujiapi". VI. Studies on the Aglycones of Steroidal Glycosides of Bei-Wujiapi (2)
MIYAHARA et al. Structure of tokoronin
Kamano et al. Steroids and related natural products. 89. Bufadienolides. 29. Synthetic routes to bufotalin
KIKUCHI et al. Studies on the Constituents of Orchidaceous Plants. III. Isolation of Non-conventional Side Chain Sterols from Nervilia purpurea SCHLECHTER and Structure Determination of Nervisterol
Iida et al. Potential bile acid metabolites. XVIII. Synthesis of stereoisomeric 3, 6, 12 alpha-trihydroxy-5 beta-cholanoic acids
Feder Essentials of steroid structure, nomenclature, reactions, biosynthesis, and measurements
Fennessey et al. Progesterone metabolism in T47Dco human breast cancer cells—I. 5α-pregnan-3β, 6α-diol-20-one is the secreted product
Hoff Steroid rearrangements. Reactions of a 16, 17. alpha.-epoxypregnan-20-one with hydrogen fluoride. Thermal dehydrofluorinations
Fishman et al. Synthesis of epimeric 15-hydroxyestriols, new and potential metabolites of estradiol
Mazoir et al. Hemisynthesis of New Triterpene Derivatives using Oxidation by CrO3 and NaIO4‐(RuCl3, 3H2O)
Sauer et al. Conversion of 5α-pregnanolone to uzarigenin by Strophanthus kombé