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Carrington, 1971 - Google Patents

The development of commercial processes for the production of 6-aminopenicillanic acid (6-APA)

Carrington, 1971

Document ID
11808109980185403564
Author
Carrington T
Publication year
Publication venue
Proceedings of the Royal Society of London. Series B. Biological Sciences

External Links

Snippet

In the preceding paper Sir Ernst Chain described how the discovery of 6-APA and its subsequent conversion into a succession of therapeutically important semisynthetic penicillins has created a new international antibiotics industry. As the key raw material for …
Continue reading at royalsocietypublishing.org (other versions)

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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
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    • C12P41/00—Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007—Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
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    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
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    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
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