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Fioravanti et al., 2010 - Google Patents

Synthesis and biological evaluation of N-substituted-3, 5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors

Fioravanti et al., 2010

Document ID
11215151450408369097
Author
Fioravanti R
Bolasco A
Manna F
Rossi F
Orallo F
Ortuso F
Alcaro S
Cirilli R
Publication year
Publication venue
European journal of medicinal chemistry

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Snippet

Eighteen new 1-N-substituted-3, 5-diphenyl-2-pyrazoline derivatives have been synthesized and cyclooxygenase (COX-1 and COX-2) inhibitory activities have been evaluated. The results of these biological assays showed that all of new derivatives are not endowed with …
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