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Si et al., 2004 - Google Patents

Envelope glycoprotein determinants of increased entry in a pathogenic simian–human immunodeficiency virus (SHIV-HXBc2P 3.2) passaged in monkeys

Si et al., 2004

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Document ID
11128513503044902155
Author
Si Z
Gorry P
Babcock G
Owens C
Cayabyab M
Phan N
Sodroski J
Publication year
Publication venue
AIDS research and human retroviruses

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Snippet

Passage of a nonpathogenic simian-human immunodeficiency virus (SHIV-HXBc2) in monkeys resulted in changes in the viral envelope glycoproteins that are responsible for a dramatic increase in replication and pathogenicity in vivo. Here, we show that the envelope …
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