Mattson et al., 1993 - Google Patents
Synthesis and Biological Evaluation of New Conformationally Restricted PCP AnalogsMattson et al., 1993
- Document ID
- 10979719811450159928
- Author
- Mattson M
- De Costa B
- Linders J
- Jacobson A
- Publication year
- Publication venue
- NIDA RESEARCH MONOGRAPH
External Links
Snippet
PCP (1-(1-phenylcyclohexyl) piperidine) has been found to act as a noncompetitive antagonist for the NMDA-receptor ionophore complex. This receptor is involved in normal neuronal functions, as well as in excitotoxity and neurodegenerative diseases. In our …
- 230000015572 biosynthetic process 0 title abstract description 4
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