Griesi-Oliveira et al., 2015 - Google Patents
Modeling non-syndromic autism and the impact of TRPC6 disruption in human neuronsGriesi-Oliveira et al., 2015
View PDF- Document ID
- 10563066623924341537
- Author
- Griesi-Oliveira K
- Acab A
- Gupta A
- Sunaga D
- Chailangkarn T
- Nicol X
- Nunez Y
- Walker M
- Murdoch J
- Sanders S
- Fernandez T
- Ji W
- Lifton R
- Vadasz E
- Dietrich A
- Pradhan D
- Song H
- Ming G
- Gu X
- Haddad G
- Marchetto M
- Spitzer N
- Passos-Bueno M
- State M
- Muotri A
- Publication year
- Publication venue
- Molecular psychiatry
External Links
Snippet
An increasing number of genetic variants have been implicated in autism spectrum disorders (ASDs), and the functional study of such variants will be critical for the elucidation of autism pathophysiology. Here, we report a de novo balanced translocation disruption of …
- 108010061792 TRPC6 Cation Channel 0 title abstract description 157
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- G—PHYSICS
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- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0619—Neurons
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
- C12N5/0602—Vertebrate cells
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- C12N5/0623—Stem cells
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- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- C12N2501/606—Transcription factors c-Myc
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