[go: up one dir, main page]

Estcourt et al., 2005 - Google Patents

Vaccine route, dose and type of delivery vector determine patterns of primary CD8+ T cell responses

Estcourt et al., 2005

View PDF @Full View
Document ID
10538047742798124707
Author
Estcourt M
Létourneau S
McMichael A
Hanke T
Publication year
Publication venue
European journal of immunology

External Links

Snippet

The dynamics of primary CD8+ T cell responses following administration of modified virus Ankara (MVA)‐and DNA‐vectored vaccines was investigated in a mouse model. To overcome the low frequency of naive antigen‐specific precursors and follow the early …
Continue reading at onlinelibrary.wiley.com (PDF) (other versions)

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/21Retroviridae, e.g. equine infectious anemia virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse Transcribing RNA Viruses
    • C12N2740/00011Reverse Transcribing RNA Viruses
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV

Similar Documents

Publication Publication Date Title
Estcourt et al. Vaccine route, dose and type of delivery vector determine patterns of primary CD8+ T cell responses
US8728485B2 (en) Peptide library obtained from multi-clade chimeric immunogens derived from highly conserved regions of the human immunodeficiency virus type 1 (HIV-1) consensus proteome
Allen et al. Induction of AIDS virus-specific CTL activity in fresh, unstimulated peripheral blood lymphocytes from rhesus macaques vaccinated with a DNA prime/modified vaccinia virus Ankara boost regimen
Nabel Challenges and opportunities for development of an AIDS vaccine
US12023377B2 (en) Vaccine for use in the prophylaxis and/or treatment of a disease
ES2638577T3 (en) Adenoviral vectors encoding a pathogen or tumor antigen
Wu et al. Enhanced breadth of CD4 T-cell immunity by DNA prime and adenovirus boost immunization to human immunodeficiency virus Env and Gag immunogens
Cohen et al. Novel HIV vaccine strategies: overview and perspective
Bansal et al. Multifunctional T-cell characteristics induced by a polyvalent DNA prime/protein boost human immunodeficiency virus type 1 vaccine regimen given to healthy adults are dependent on the route and dose of administration
Excler et al. Novel directions in HIV-1 vaccines revealed from clinical trials
Lema et al. HIV vaccines: A brief overview
Vasconcelos et al. Relevance of long-lived CD8+ T effector memory cells for protective immunity elicited by heterologous prime-boost vaccination
EA037583B1 (en) Methods and compositions for inducing protective immunity against human immunodeficiency virus infection
Tatsis et al. Multiple immunizations with adenovirus and MVA vectors improve CD8+ T cell functionality and mucosal homing
JP2019162120A (en) Poxvirus-plasmodium recombinants, compositions containing such recombinants, uses thereof, and methods of making and using the same
Ondondo et al. Characterization of T-cell responses to conserved regions of the HIV-1 proteome in BALB/c mice
Feng et al. Induction of CD8+ T‐lymphocyte responses to a secreted antigen of Mycobacterium tuberculosis by an attenuated vaccinia virus
Boyer et al. DNA prime Listeria boost induces a cellular immune response to SIV antigens in the rhesus macaque model that is capable of limited suppression of SIV239 viral replication
Roshorm et al. T cells induced by recombinant chimpanzee adenovirus alone and in prime‐boost regimens decrease chimeric E co HIV/NDK challenge virus load
McKee et al. Immune responses against SIV envelope glycoprotein, using recombinant SV40 as a vaccine delivery vector
Roshorm et al. Novel HIV‐1 clade B candidate vaccines designed for HLA‐B* 5101+ patients protected mice against chimaeric ecotropic HIV‐1 challenge
WO2005047483A2 (en) Renta: an hiv immunogen and uses thereof
Estcourt et al. Altered primary CD8+ T cell response to a modified virus Ankara (MVA)‐vectored vaccine in the absence of CD4+ T cell help
Überla Efficacy of AIDS vaccine strategies in nonhuman primates
Ravanfar et al. HIV vaccines under study