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Moon et al., 2005 - Google Patents

Synthesis of O-(3-[18 F] Fluoropropyl)-L-tyrosine (L-[18 F] FPT) and Its Biological Evaluation in 9L Tumor Bearing Rat

Moon et al., 2005

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Document ID
10429548784697784269
Author
Moon B
Kim S
Lee T
Ahn S
Lee K
An G
Yang S
Chi D
Choi C
Lim S
Chun K
Publication year
Publication venue
Bulletin of the Korean Chemical Society

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Snippet

Abstract O-(3-[$^{18} $ F] Fluoropropyl)-L-tyrosine (L-[$^{18} $ F] FPT) was synthesized by nucleophilic radiofluorination followed by acidic hydrolysis of protective groups and evaluated with 9 L tumor bearing rat. L-[$^{18} $ F] FPT is an homologue of O-(2-[$^{18} $ F] …
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    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0453Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K51/0455Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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