Ortega, 2010 - Google Patents
Study and characterization of dual-function affinity chromatographic adsorbents having size exclusion and adsorption properties to isolate, purify and recover small …Ortega, 2010
- Document ID
- 10386048311972414012
- Author
- Ortega O
- Publication year
External Links
Snippet
In this work, the main emphasis of the research concerns the development of isolation and purification methods of biomolecules from biological fluids. Several separation techniques were incorporated in chromatographic gels to obtain multifunctional hybrid chromatographic …
- 239000002831 pharmacologic agent 0 title abstract description 18
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
- B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3847—Multimodal interactions
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1974215B1 (en) | Affinity chromatography matrices and methods of making and using the same | |
| Li et al. | Affinity monolith chromatography: A review of general principles and applications | |
| Pfaunmiller et al. | Affinity monolith chromatography: a review of principles and recent analytical applications | |
| Gutierrez et al. | Immobilized metal‐ion affinity chromatography: status and trends | |
| US20220098233A1 (en) | Mixed Bed Ion Exchange Adsorber | |
| US9155980B2 (en) | Separation medium for chromatography of various biomolecules | |
| JP5826180B2 (en) | Separation matrix | |
| EP2841177A1 (en) | Separation method and separation matrix | |
| KR20160054597A (en) | Novel antibody purification method and antibody obtained therefrom, and novel antibody purification method using cation exchanger and antibody obtained therefrom | |
| JP2015501310A (en) | Solid phase for mixed-mode chromatographic purification of proteins | |
| EP2894159A1 (en) | Mix-mode antibody affinity separation matrix and purification method using same, and target molecule | |
| Khan et al. | Alginate dialdehyde meets nylon membrane: a versatile platform for facile and green fabrication of membrane adsorbers | |
| González-Ortega et al. | Adsorption of peptides and small proteins with control access polymer permeation to affinity binding sites. Part I: Polymer permeation-immobilized metal ion affinity chromatography separation adsorbents with polyethylene glycol and immobilized metal ions | |
| Ortega | Study and characterization of dual-function affinity chromatographic adsorbents having size exclusion and adsorption properties to isolate, purify and recover small biomolecules from complex biological mixtures | |
| González-Ortega et al. | Adsorption of peptides and small proteins with control access polymer permeation to affinity binding sites. Part II: Polymer permeation-ion exchange separation adsorbents with polyethylene glycol and strong anion exchange groups | |
| JP4146838B2 (en) | Separation method by adsorption | |
| González-Ortega et al. | Purification of human serum immunoglobulins using immobilized metal affinity chromatography with ethylenediamine triacetic acid as chelating agent | |
| Horak et al. | Performance evaluation of Mimetic Ligand™ B14-triazole-FractoAIMs adsorbents for the capture of human monoclonal immunoglobulin G from cell culture feed | |
| JP2006026607A (en) | Adsorbent for affinity chromatography | |
| Borsoi‐Ribeiro et al. | Behavior of human immunoglobulin G adsorption onto immobilized Cu (II) affinity hollow‐fiber membranes | |
| CN118922247A (en) | Alkali-stable kappa light chain binding separation matrix | |
| WO2023064949A1 (en) | Mixed mode cationic exchange chromatography ligands based on substituted 2-benzamido acetic acid structures | |
| Polakovic | Influence of ligand density on antibody binding capacity of cation-exchange adsorbents |