[go: up one dir, main page]

Skiba et al., 2023 - Google Patents

Replacement of the phosphodiester backbone between canonical nucleosides with a dirhenium carbonyl “click” linker—a new class of luminescent organometallic …

Skiba et al., 2023

Document ID
10364888818700274811
Author
Skiba J
Kowalczyk A
Gorski A
Dutkiewicz N
Gapińska M
Stróżek J
Woźniak K
Trzybiński D
Kowalski K
Publication year
Publication venue
Dalton Transactions

External Links

Snippet

The first-in-class luminescent dinucleoside phosphate analogs with a [Re2 (μ-Cl) 2 (CO) 6 (μ- pyridazine)]“click” linker as a replacement for the natural phosphate group are reported together with the synthesis of luminescent adenosine and thymidine derivatives having the …
Continue reading at pubs.rsc.org (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00—Metallocenes
    • C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic System
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P-C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Similar Documents

Publication Publication Date Title
Takezawa et al. Artificial DNA base pairing mediated by diverse metal ions
Skiba et al. Replacement of the phosphodiester backbone between canonical nucleosides with a dirhenium carbonyl “click” linker—a new class of luminescent organometallic dinucleoside phosphate mimics
Lietard et al. New strategies for cyclization and bicyclization of oligonucleotides by click chemistry assisted by microwaves
US6914148B2 (en) Guanidinium functionalized intermediates
Kowalski et al. The synthesis, structure, electrochemistry and in vitro anticancer activity studies of ferrocenyl-thymine conjugates
Largy et al. Tridentate N‐Donor Palladium (II) Complexes as Efficient Coordinating Quadruplex DNA Binders
Štarha et al. How to modify 7-azaindole to form cytotoxic Pt (II) complexes: Highly in vitro anticancer effective cisplatin derivatives involving halogeno-substituted 7-azaindole
Palepu et al. Synthesis and evaluation of new salicylaldehyde-2-picolinylhydrazone Schiff base compounds of Ru (II), Rh (III) and Ir (III) as in vitro antitumor, antibacterial and fluorescence imaging agents
Alagesan et al. An investigation on new ruthenium (II) hydrazone complexes as anticancer agents and their interaction with biomolecules
Panaka et al. Ferrocenyl chalcogeno (sugar) triazole conjugates: Synthesis, characterization and anticancer properties
Albert et al. Cyclopalladated benzophenone imines: Synthesis, cytotoxicity against human breast adenocarcinoma cell lines and DNA interaction
Scharf et al. Sequence‐Dependent Duplex Stabilization upon Formation of a Metal‐Mediated Base Pair
Aro-Heinila et al. 3-fluoro-2-mercuri-6-methylaniline nucleotide as a high-affinity nucleobase-specific hybridization probe
Patel et al. Nucleic acid interaction and antibacterial behaviours of a ternary palladium (II) complexes
Al-Rashdi et al. Tuning anticancer properties and DNA-binding of Pt (II) complexes via alteration of nitrogen softness/basicity of tridentate ligands
Lesnikowski DNA as platform for new biomaterials. Metal-containing nucleic acids
D'Anna et al. Salphen metal complexes as potential anticancer agents: interaction profile and selectivity studies toward the three G-quadruplex units in the KIT promoter
Liang et al. Study on nucleic acid (CT-DNA and yeast tRNA) binding behaviors and cytotoxic properties of a heterodinuclear Ru (II)–Co (III) polypyridyl complex
Skiba et al. Luminescent pyrenyl-GNA nucleosides: synthesis, photophysics and confocal microscopy studies in cancer HeLa cells
Vekariya et al. Evolution of rhodium (III) and iridium (III) chelates as metallonucleases
Wang et al. Synthesis and crystal structure of a new copper (II) complex with N, N′-(4, 4′-bithiazole-2, 2′-diyl) diacetimidamide as ligand: Molecular docking, DNA-binding and cytotoxicity activity studies
Dileepan et al. Killing effects of Candida albicans through alteration of cellular morphology and growth metabolism using Tris-NHC ligand coordinated to AgI and CuI
Roy et al. DNA cleavage and antitumour activity of platinum (II) and copper (II) compounds derived from 4-methyl-2-N-(2-pyridylmethyl) aminophenol: spectroscopic, electrochemical and biological investigation
Tabassum et al. Synthesis of Aryl-1, 2, 4, 5-tetrazinane-3-thiones, in vitro DNA binding studies, nuclease activity and its antimicrobial activity
Klarek et al. Chemistry of organometallic nucleic acid components: personal perspectives and prospects for the future