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ZA983177B - 5,7-Disubstituted-4-aminopyrdo [2,3] pyrimidine compounds - Google Patents

5,7-Disubstituted-4-aminopyrdo [2,3] pyrimidine compounds

Info

Publication number
ZA983177B
ZA983177B ZA983177A ZA983177A ZA983177B ZA 983177 B ZA983177 B ZA 983177B ZA 983177 A ZA983177 A ZA 983177A ZA 983177 A ZA983177 A ZA 983177A ZA 983177 B ZA983177 B ZA 983177B
Authority
ZA
South Africa
Prior art keywords
aminopyrdo
disubstituted
pyrimidine compounds
pyrimidine
compounds
Prior art date
Application number
ZA983177A
Inventor
Shripad S Bhagwat
Chih-Hung Lee
Marlon Daniel Cowart
Jeffrey Mckie
Anne Laure Grillot
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of ZA983177B publication Critical patent/ZA983177B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA983177A 1997-04-16 1998-04-15 5,7-Disubstituted-4-aminopyrdo [2,3] pyrimidine compounds ZA983177B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83821697A 1997-04-16 1997-04-16

Publications (1)

Publication Number Publication Date
ZA983177B true ZA983177B (en) 1999-01-22

Family

ID=25276561

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA983177A ZA983177B (en) 1997-04-16 1998-04-15 5,7-Disubstituted-4-aminopyrdo [2,3] pyrimidine compounds

Country Status (18)

Country Link
EP (1) EP0989986A1 (en)
JP (1) JP2001520655A (en)
KR (1) KR20010006509A (en)
CN (1) CN1252070A (en)
AR (1) AR012436A1 (en)
AU (1) AU7108398A (en)
BG (1) BG103842A (en)
BR (1) BR9809055A (en)
CA (1) CA2286909A1 (en)
CO (1) CO4940446A1 (en)
HU (1) HUP0001434A3 (en)
IL (1) IL131618A0 (en)
NO (1) NO995036L (en)
PL (1) PL336304A1 (en)
SK (1) SK141799A3 (en)
TR (1) TR199902455T2 (en)
WO (1) WO1998046605A1 (en)
ZA (1) ZA983177B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000023444A1 (en) * 1998-10-21 2000-04-27 Abbott Laboratories 5,7-disubstituted-4-aminopyrido[2,3-d]pyrimidine compounds
ATE305303T1 (en) 2001-02-12 2005-10-15 Hoffmann La Roche 6-SUBSTITUTED PYRIDOPYRIMIDINES
JP2005526714A (en) 2002-01-17 2005-09-08 ニューロジェン・コーポレーション Substituted quinazolin-4-ylamine analogs as modulators of capsaicin
DE10335183A1 (en) * 2003-07-30 2005-02-24 Bayer Cropscience Ag Fungicidal drug combinations
JP4880684B2 (en) * 2005-07-21 2012-02-22 エフ．ホフマン−ラ ロシュ アーゲー Pyrido [2,3-D] pyrimidine-2,4-diamine compounds as PTP1B inhibitors
EP1971611B1 (en) 2005-12-21 2012-10-10 Abbott Laboratories Anti-viral compounds
ATE541844T1 (en) * 2005-12-21 2012-02-15 Abbott Lab ANTIVIRAL COMPOUNDS
EP2094276A4 (en) 2006-12-20 2011-01-05 Abbott Lab Anti-viral compounds
CA2696609C (en) 2007-08-27 2017-09-05 Helicon Therapeutics, Inc. Therapeutic isoxazole compounds
MX2010002098A (en) 2007-08-31 2010-03-30 Eisai R&D Man Co Ltd Polycyclic compound.
DE102007061764A1 (en) * 2007-12-20 2009-06-25 Bayer Healthcare Ag Anellated cyanopyridines and their use
CN102333777B (en) * 2009-02-26 2014-06-25 卫材R&D管理有限公司 Nitrogen-containing fused heterocyclic compounds and their use as beta amyloid production inhibitors
WO2014055595A1 (en) 2012-10-05 2014-04-10 Merck Sharp & Dohme Corp. Indoline compounds as aldosterone synthase inhibitiors related applications
EP3436434B1 (en) 2016-03-31 2020-07-08 Oncternal Therapeutics, Inc. Indoline analogs and uses thereof
CN110256420B (en) * 2019-05-07 2020-04-28 江西中医药大学 Tetrahydropyridopyrimidine derivatives and preparation methods and uses thereof
CN110283171A (en) * 2019-07-17 2019-09-27 鼎泰(南京)临床医学研究有限公司 Compound of the one kind containing Pyridopyrimidine -4- amine structure, pharmaceutical composition and its application

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5324731A (en) * 1989-02-14 1994-06-28 Amira, Inc. Method of inhibiting transformation of cells in which purine metabolic enzyme activity is elevated
IL112249A (en) * 1994-01-25 2001-11-25 Warner Lambert Co Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
US6143749A (en) * 1995-06-07 2000-11-07 Abbott Laboratories Heterocyclic substituted cyclopentane compounds

Also Published As

Publication number Publication date
CA2286909A1 (en) 1998-10-22
NO995036D0 (en) 1999-10-15
AU7108398A (en) 1998-11-11
BG103842A (en) 2000-06-30
KR20010006509A (en) 2001-01-26
IL131618A0 (en) 2001-01-28
PL336304A1 (en) 2000-06-19
AR012436A1 (en) 2000-10-18
TR199902455T2 (en) 2000-01-21
NO995036L (en) 1999-10-15
BR9809055A (en) 2000-08-08
CN1252070A (en) 2000-05-03
CO4940446A1 (en) 2000-07-24
JP2001520655A (en) 2001-10-30
WO1998046605A1 (en) 1998-10-22
HUP0001434A2 (en) 2000-10-28
SK141799A3 (en) 2000-08-14
EP0989986A1 (en) 2000-04-05
HUP0001434A3 (en) 2001-01-29

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