[go: up one dir, main page]

ZA982335B - Salt of naphthyridine carboxylic acid derivative. - Google Patents

Salt of naphthyridine carboxylic acid derivative.

Info

Publication number
ZA982335B
ZA982335B ZA9802335A ZA982335A ZA982335B ZA 982335 B ZA982335 B ZA 982335B ZA 9802335 A ZA9802335 A ZA 9802335A ZA 982335 A ZA982335 A ZA 982335A ZA 982335 B ZA982335 B ZA 982335B
Authority
ZA
South Africa
Prior art keywords
salt
carboxylic acid
acid derivative
naphthyridine carboxylic
naphthyridine
Prior art date
Application number
ZA9802335A
Other languages
English (en)
Inventor
Ae Ri Kim
Jin Hwa Lee
Ki Sook Park
Jong Ryoo Choi
Tae Hee Lee
Jay Hyok Chang
Do Hyun Nam
Hoon Choi
Original Assignee
Lg Chemical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Chemical Ltd filed Critical Lg Chemical Ltd
Publication of ZA982335B publication Critical patent/ZA982335B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01Sulfonic acids
    • C07C309/02Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/04Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA9802335A 1997-03-21 1998-03-19 Salt of naphthyridine carboxylic acid derivative. ZA982335B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR19970009840 1997-03-21

Publications (1)

Publication Number Publication Date
ZA982335B true ZA982335B (en) 1999-11-23

Family

ID=19500439

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9802335A ZA982335B (en) 1997-03-21 1998-03-19 Salt of naphthyridine carboxylic acid derivative.

Country Status (39)

Country Link
US (9) US7700617B2 (fr)
EP (2) EP1179533B1 (fr)
JP (3) JP3759962B2 (fr)
KR (1) KR100266499B1 (fr)
CN (1) CN1131229C (fr)
AP (1) AP1331A (fr)
AR (1) AR012125A1 (fr)
AT (2) ATE257836T1 (fr)
AU (1) AU726634B2 (fr)
BG (1) BG63972B1 (fr)
BR (1) BR9808290A (fr)
CA (1) CA2283671C (fr)
CZ (2) CZ288673B6 (fr)
DE (2) DE69814378T2 (fr)
DK (2) DK0981527T3 (fr)
DZ (1) DZ2448A1 (fr)
EA (1) EA001674B1 (fr)
ES (2) ES2213669T3 (fr)
HK (1) HK1026698A1 (fr)
HU (2) HU225412B1 (fr)
ID (1) ID22681A (fr)
IL (2) IL131812A0 (fr)
IN (1) IN188178B (fr)
IS (2) IS2093B (fr)
MA (1) MA24500A1 (fr)
MY (1) MY137653A (fr)
NO (1) NO312515B1 (fr)
NZ (1) NZ337748A (fr)
OA (1) OA11161A (fr)
PE (1) PE67999A1 (fr)
PL (1) PL191815B1 (fr)
PT (2) PT1179533E (fr)
SA (1) SA98181055B1 (fr)
SI (2) SI0981527T1 (fr)
SK (1) SK284107B6 (fr)
TR (1) TR199902313T2 (fr)
UA (1) UA56218C2 (fr)
WO (1) WO1998042705A1 (fr)
ZA (1) ZA982335B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9820405D0 (en) 1998-09-18 1998-11-11 Smithkline Beecham Plc Process
EP1169027A4 (fr) * 1999-03-19 2004-10-20 Abbott Gmbh & Co Kg Traitement de l'arthrose
US6331550B1 (en) 1999-06-29 2001-12-18 Smithkline Beecham Corporation Methods of use of quinolone compounds against anaerobic pathogenic bacteria
US6262071B1 (en) 1999-06-29 2001-07-17 Smithkline Beecham Corporation Methods of use of antimicrobial compounds against pathogenic amycoplasma bacteria
US6803376B1 (en) 1999-06-29 2004-10-12 Smithkline Beecham Corporation Method of use of quinolone compounds against pneumococcal and haemophilus bacteria
CA2282066C (fr) 1999-06-29 2010-09-07 Smithkline Beecham Corporation Methodes d'utilisation de composes de quinolone contre des bacteries pathogenes atypiques dans les voies respiratoires superieures
GB9920917D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel process
GB9920919D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel compound
JP2001097891A (ja) * 1999-09-24 2001-04-10 Smithkline Beecham Corp 呼吸器系病原菌に対するフルオロキノロン化合物の使用法
JP2001097864A (ja) * 1999-09-24 2001-04-10 Smithkline Beecham Corp 呼吸管および尿路病原性細菌に対するフルオロキノリン化合物の使用方法
GR1003520B (el) * 1999-09-22 2001-01-22 Smithkline Beecham Plc Μεθοδος χρησης ενωσεων φλουοροκινολονης εναντια σε νοσοκομειακα αρνητικα κατα gramμ παθογενων βακτηριδιων
AU7709400A (en) * 1999-09-22 2001-04-24 Smithkline Beecham Corporation Methods of use of fluoroquinolone compounds against bacteria
JP2001097863A (ja) * 1999-09-24 2001-04-10 Smithkline Beecham Corp 嫌気性病原菌に対するフルオロキノロン化合物の使用法
GR1003521B (el) * 1999-09-23 2001-01-22 Smithkline Beecham Plc Μεθοδοι χρησεως ενωσεων φλουοροκινολονης εναντια κατα gram θετικων παθογονων βακτηριδιων
KR20010091379A (ko) * 2000-03-15 2001-10-23 성재갑 7-(4-아미노메틸-3-옥심)피롤리딘 치환체를 갖는 퀴놀린카르복실산 유도체의 신규 제조방법
DK1412078T3 (da) 2001-08-02 2009-02-02 Lg Life Sciences Ltd Fremgangsmåde til fremstilling af amino-beskyttede derivater af 4-aminomethylen-pyrrolidin-3-on, Gemifloxacin eller salte deraf
EP1458391B1 (fr) * 2001-11-30 2007-09-05 LG Life Sciences Ltd. Methode de traitement des infections bacteriennes a l'aide de gemifloxacine ou d'un sel de celle-ci et d'une beta-lactamine
KR100517638B1 (ko) * 2002-04-08 2005-09-28 주식회사 엘지생명과학 게미플록사신 산염의 새로운 제조방법
AR043880A1 (es) * 2003-04-22 2005-08-17 Solvay Pharm Gmbh Mesilato acido de 4-(4.trans-hidroxiciclohexil) amino-2-fenil-7h-pirrolo (2,3-d) pirimidina y sus formas polimorfas
EP2161270A1 (fr) 2005-06-15 2010-03-10 Hetero Drugs Limited Hydrates de gémifloxacin
MX2008011376A (es) * 2006-03-07 2009-02-06 Wockhardt Ltd Profarmacos de acido benzoquinolizin-2-carboxilico.
WO2010001408A2 (fr) * 2008-06-06 2010-01-07 Matrix Laboratories Ltd. Nouvelles formes polymorphes du mésylate de gémifloxacine
WO2010146594A1 (fr) * 2009-06-16 2010-12-23 Hetero Research Foundation Nouveaux polymorphes de mésylate de gémifloxacine
EP2491921A1 (fr) * 2011-02-25 2012-08-29 Deva Holding Anonim Sirketi Conservation de la forme anhydre de gemifloxacine
ES2746031T3 (es) * 2012-02-27 2020-03-04 Bristol Myers Squibb Co Sal de N-(5S,6S,9R)-5-amino-6-(2,3-difluorofenil)-6,7,8,9-tetrahidro-5H-ciclohepta[B]piridin-9-IL-4-(2-oxo-2,3-dihidro-1H-imidazo[4,5-B]piridin-1-il)piperidina-1-carboxilato
CZ2016104A3 (cs) * 2016-02-24 2017-09-06 Zentiva, K.S. Krystalické modifikace solí methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}fenyl)amino](fenyl)methyliden}-2-oxo-2,3-dihydro-1H-indol-6-karboxylátu a způsoby jejich přípravy

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR223983A1 (es) 1978-08-25 1981-10-15 Dainippon Pharmaceutical Co Un procedimiento para-preparar derivados de acido 6-halogeno-4-oxo-7-(1-piperazinil)-1,8-naftiridin-3-carboxilico
ES8304117A1 (es) 1981-06-11 1983-02-16 Warner Lambert Co "un procedimiento para preparar sales de compuestos de naftiridina y quinoleina".
IN162769B (fr) 1984-11-13 1988-07-09 Kyorin Seiyaku Kk
NZ222047A (en) 1986-10-08 1991-01-29 Bristol Myers Co Quinoline - or naphthyridine - carboxylic acid anti-bacterial agents
JPH01100165A (ja) 1987-10-13 1989-04-18 Shionogi & Co Ltd オキシムまたはヒドロキシアミン誘導体系抗菌剤
US4920120A (en) 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
US4931446A (en) * 1988-03-23 1990-06-05 Abbott Laboratories Antimicrobial for in-vitro diagnostic kits
US5286723A (en) * 1988-08-31 1994-02-15 Daiichi Seiyaku Co., Ltd. Spiro compound
CA1336090C (fr) * 1988-08-31 1995-06-27 Isao Hayakawa Amines cycliques a substituant spiro de derives de la quinolone
PL166381B1 (pl) 1989-08-16 1995-05-31 Pfizer Sposób wytwarzania nowych podstawionych kwasów 7-azabicyklochinolonokarboksylowych PL PL PL PL
EP0541086A1 (fr) 1991-11-08 1993-05-12 Kaken Pharmaceutical Co., Ltd. Fluoro-6-chinolones antibactériennes ayant un groupe oxime sur le substituant en position 7
WO1993025545A1 (fr) 1992-06-09 1993-12-23 Korea Research Institute Of Chemical Technology Nouveaux derives de quinoleine et procedes pour leur preparation
DK0688772T3 (da) * 1994-06-16 1999-11-01 Lg Chemical Ltd Quinolincarboxylsyrederivater med 7-(4-aminomethyl-3-oxim)-pyrrolidinsubstituenter og fremgangsmåde til deres fremstilling
US5776944A (en) * 1994-06-16 1998-07-07 Lg Chemical Ltd. 7-(4-aminomethyl-3-methyloxyiminopyrroplidin-1-yl)-1-cyclopropyl-6-flu oro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid and the process for the preparation thereof
EP0787720B1 (fr) 1994-10-20 2003-07-16 Wakunaga Seiyaku Kabushiki Kaisha Derive de pyridone-carboxylate, ou sel de celui-ci, et antibacterien le contenant comme principe actif
AU5260096A (en) 1995-01-30 1996-08-21 Wakunaga Seiyaku Kabushiki Kaisha Novel pyridonecarboxylic acid derivatives or salts thereof and antibacterial agent containing the same as active ingredient
ES2117426T3 (es) 1995-06-06 1998-08-01 Pfizer Forma cristalina de la sal anhidra compuesta de los acidos 7-((1a,5a,6a)-6-amino-3-azabiciclo(3.1.0.)hex-3-il)-6-fluoro-1-(2,4-difluorofenil)-1,4-dihidro-4-oxo-1,8-naftiridina-3-carboxilico y metanosulfonico.
US20020032216A1 (en) * 1997-03-21 2002-03-14 Lg Chemical Ltd. Salt of naphthyridine carboxylic acid derivative
KR100286874B1 (ko) * 1998-03-04 2001-04-16 성재갑 보호된 4-아미노메틸-피롤리딘-3-온의 제조방법
GB9820405D0 (en) 1998-09-18 1998-11-11 Smithkline Beecham Plc Process

Also Published As

Publication number Publication date
ID22681A (id) 1999-12-09
IS5181A (is) 1999-09-14
EP1179533B1 (fr) 2004-01-14
ATE239724T1 (de) 2003-05-15
JP2000510484A (ja) 2000-08-15
IN188178B (fr) 2002-08-31
BG103750A (en) 2000-06-30
CZ328299A3 (cs) 2000-02-16
HUP0600401A3 (en) 2010-05-28
US20080039488A1 (en) 2008-02-14
US20110312987A1 (en) 2011-12-22
DE69814378T2 (de) 2004-02-26
JP2009051851A (ja) 2009-03-12
DK1179533T3 (da) 2004-05-03
CA2283671A1 (fr) 1998-10-01
ES2198697T3 (es) 2004-02-01
PT981527E (pt) 2003-09-30
HUP0000728A3 (en) 2002-12-28
HU227536B1 (en) 2011-08-29
SI1179533T1 (en) 2004-04-30
NO312515B1 (no) 2002-05-21
TR199902313T2 (xx) 1999-12-21
HUP0000728A2 (hu) 2000-09-28
JP4781614B2 (ja) 2011-09-28
NO994595D0 (no) 1999-09-21
AP1331A (en) 2004-11-26
KR100266499B1 (ko) 2000-12-01
HK1026698A1 (en) 2000-12-22
ES2213669T3 (es) 2004-09-01
PL191815B1 (pl) 2006-07-31
SK123699A3 (en) 2000-08-14
EP0981527B1 (fr) 2003-05-07
MY137653A (en) 2009-02-27
HU0600401D0 (en) 2006-07-28
NO994595L (no) 1999-09-21
US20090182006A1 (en) 2009-07-16
DZ2448A1 (fr) 2003-01-11
JP2004002413A (ja) 2004-01-08
PL335812A1 (en) 2000-05-22
EP1179533A2 (fr) 2002-02-13
SK284107B6 (sk) 2004-09-08
IL131812A0 (en) 2001-03-19
WO1998042705A1 (fr) 1998-10-01
AU726634B2 (en) 2000-11-16
HU225412B1 (en) 2006-11-28
CZ288673B6 (cs) 2001-08-15
US20160264569A1 (en) 2016-09-15
AP9901649A0 (en) 1999-09-30
BG63972B1 (bg) 2003-08-29
PE67999A1 (es) 1999-09-30
ATE257836T1 (de) 2004-01-15
DK0981527T3 (da) 2003-09-01
EA199900855A1 (ru) 2000-04-24
US20100240694A1 (en) 2010-09-23
CN1131229C (zh) 2003-12-17
BR9808290A (pt) 2000-05-16
US20170253588A1 (en) 2017-09-07
US20150291585A1 (en) 2015-10-15
DE69821147D1 (de) 2004-02-19
EP0981527A1 (fr) 2000-03-01
US7700617B2 (en) 2010-04-20
CN1251101A (zh) 2000-04-19
CZ288715B6 (cs) 2001-08-15
NZ337748A (en) 2001-03-30
AR012125A1 (es) 2000-09-27
IS7952A (is) 2005-07-21
SI0981527T1 (en) 2003-10-31
DE69821147T2 (de) 2004-11-11
DE69814378D1 (de) 2003-06-12
KR19980080504A (ko) 1998-11-25
IS2093B (is) 2006-04-12
UA56218C2 (uk) 2003-05-15
PT1179533E (pt) 2004-05-31
EA001674B1 (ru) 2001-06-25
CA2283671C (fr) 2003-09-16
MA24500A1 (fr) 1998-10-01
US20140187576A1 (en) 2014-07-03
IS2095B (is) 2006-04-12
AU6636698A (en) 1998-10-20
IL131812A (en) 2006-04-10
EP1179533A3 (fr) 2002-03-20
SA98181055B1 (ar) 2006-10-11
OA11161A (en) 2003-04-25
JP3759962B2 (ja) 2006-03-29
US20130065917A1 (en) 2013-03-14

Similar Documents

Publication Publication Date Title
ZA982335B (en) Salt of naphthyridine carboxylic acid derivative.
HK1043124A1 (en) Salt of naphthyridine carboxylic acid derivative.
PL334997A1 (en) Derivatives or arylosulphonyl-hydroxamic acid
HK1039939A1 (zh) α-取代羧酸衍生物
HU9801044D0 (en) Sulfonyl-amino-carboxylic acid derivatives
HUP0003881A3 (en) Amidocarboxylic acid derivatives
HUP9902645A3 (en) Fused-ring carboxylic acid derivatives
AU2006699A (en) Phosphinic alkanoic acid derivatives
HUP9901966A3 (en) Quinolonecarboxylic acid derivatives or salts thereof
ZA9810298B (en) Isothiazole carboxylic acid derivatives
AU7940598A (en) Quinolone carboxylic acid derivatives
IL129135A0 (en) 3-Alkoxyisoxazol-4- YL-substituted 2-amino carboxylic acid compounds
AU697025B2 (en) Quinoline carboxylic acid
HUT75640A (en) Novel quinolone carboxylic acid derivatives
PL335601A1 (en) Derivatives of 2-substituted benzoylcycloalkyl carboxylic acid
IL123213A0 (en) Carboxylic acid derivatives
GB2318789B (en) Carboxylic acid derivatives,method of manufacturing the same and therapeutic agents containing these compounds
HRP940833A2 (en) 1-(2-fluorocyclopropyl)-quinoline- and naphthyridone carboxylic acid derivatives
GB9907082D0 (en) The preparation of carboxylic acid derivatives
AU3076295A (en) Heterocyclyl-1-phenyl substituted quinolone carboxylic acids as antiviral agents
AU6516998A (en) Lipid a1-position carboxylic acid derivatives
ZA976429B (en) Benzoylpropionic acid ester derivatives.
SI0934286T1 (en) 3-alkoxyisoxazol-4-yl-substituted 2-amino carboxylic acid compounds
GB9306448D0 (en) Carboxylic acid derivatives
GB9325620D0 (en) Carboxylic acid derivatives