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ZA977493B - Optically active compounds - Google Patents

Optically active compounds

Info

Publication number
ZA977493B
ZA977493B ZA977493A ZA977493A ZA977493B ZA 977493 B ZA977493 B ZA 977493B ZA 977493 A ZA977493 A ZA 977493A ZA 977493 A ZA977493 A ZA 977493A ZA 977493 B ZA977493 B ZA 977493B
Authority
ZA
South Africa
Prior art keywords
optically active
active compounds
optically
compounds
active
Prior art date
Application number
ZA977493A
Other languages
English (en)
Inventor
Marc Gerspacher
Andreas Von Sprecher
Robert Mah
Silvio Roggo
Stefan Stutz
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ZA977493B publication Critical patent/ZA977493B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/12—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA977493A 1996-08-22 1997-08-21 Optically active compounds ZA977493B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH206196 1996-08-22

Publications (1)

Publication Number Publication Date
ZA977493B true ZA977493B (en) 1998-08-03

Family

ID=4225003

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA977493A ZA977493B (en) 1996-08-22 1997-08-21 Optically active compounds

Country Status (32)

Country Link
US (1) US6319917B1 (cs)
EP (1) EP0923550B1 (cs)
JP (1) JP3654908B2 (cs)
KR (1) KR100467402B1 (cs)
CN (1) CN1119328C (cs)
AR (1) AR009266A1 (cs)
AT (1) ATE224875T1 (cs)
AU (1) AU721850B2 (cs)
BR (1) BR9711350A (cs)
CA (1) CA2264065C (cs)
CO (1) CO4900047A1 (cs)
CZ (1) CZ294233B6 (cs)
DE (1) DE69715886T2 (cs)
DK (1) DK0923550T3 (cs)
ES (1) ES2184083T3 (cs)
HK (1) HK1021372A1 (cs)
HU (1) HU226395B1 (cs)
ID (1) ID18059A (cs)
IL (1) IL128631A (cs)
MY (1) MY132550A (cs)
NO (1) NO312292B1 (cs)
NZ (1) NZ334736A (cs)
PE (1) PE107498A1 (cs)
PL (1) PL193731B1 (cs)
PT (1) PT923550E (cs)
RU (1) RU2185375C2 (cs)
SI (1) SI0923550T1 (cs)
SK (1) SK283991B6 (cs)
TR (1) TR199900363T2 (cs)
TW (1) TW438777B (cs)
WO (1) WO1998007694A1 (cs)
ZA (1) ZA977493B (cs)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6281300B1 (en) * 1998-03-20 2001-08-28 Exxon Chemical Patents, Inc. Continuous slurry polymerization volatile removal
GB0010958D0 (en) * 2000-05-05 2000-06-28 Novartis Ag Organic compounds
GB0203061D0 (en) * 2002-02-08 2002-03-27 Novartis Ag Organic compounds
GB0224788D0 (en) * 2002-10-24 2002-12-04 Novartis Ag Organic compounds
GB2394417A (en) * 2002-10-24 2004-04-28 Novartis Ag Solid dispersion comprising a piperidine substance P antagonist and a carrier
BRPI0415923A (pt) * 2003-10-27 2006-12-26 Novartis Ag uso de antagonistas de neuroquinina no tratamento de incontigência urinária
CN103393691A (zh) * 2003-12-01 2013-11-20 剑桥企业有限公司 抗炎药
GB0402679D0 (en) * 2004-02-06 2004-03-10 Novartis Ag Organic compounds
JO2630B1 (en) 2006-04-13 2012-06-17 نوفارتيس ايه جي Organic compounds
GB0607532D0 (en) * 2006-04-13 2006-05-24 Novartis Ag Organic compounds
EP1938804A1 (en) * 2006-12-22 2008-07-02 Novartis AG Pharmaceutical formulation comprising neurokinin antagonist
JP2010516731A (ja) 2007-01-24 2010-05-20 グラクソ グループ リミテッド ２−メトキシ−５−（５−トリフルオロメチル−テトラゾール−１−イル）−ベンジル］−（２ｓ−フェニル−ピペリジン−３ｓ−イル）−アミンを含む医薬組成物
UA105182C2 (ru) 2008-07-03 2014-04-25 Ньюрексон, Інк. Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность
MX2011008878A (es) * 2009-02-24 2011-09-21 Novartis Ag Usos de antagonistas de los receptores de nk.
RU2697414C1 (ru) * 2018-05-11 2019-08-14 Общество с ограниченной ответственностью "АЙ БИ ДИ Терапевтикс" Новый антагонист тахикининовых рецепторов и его применение

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2110514A1 (en) 1991-07-05 1993-01-21 Raymond Baker Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
MY110227A (en) * 1991-08-12 1998-03-31 Ciba Geigy Ag 1-acylpiperindine compounds.
US5217996A (en) 1992-01-22 1993-06-08 Ciba-Geigy Corporation Biaryl substituted 4-amino-butyric acid amides
EP0716077A1 (de) * 1994-12-08 1996-06-12 Ciba-Geigy Ag Aromatisch substituierte Omega-Aminoalkansäureamide und Alkansäurediamide und ihre Verwendung als Renininhibitoren
NZ300942A (en) 1995-02-22 1998-12-23 Novartis Ag 1-aryl-2-acylamino-ethane derivatives as neurokinin 1 antagonists

Also Published As

Publication number Publication date
AU721850B2 (en) 2000-07-13
EP0923550A1 (en) 1999-06-23
US6319917B1 (en) 2001-11-20
NO312292B1 (no) 2002-04-22
HUP0001165A3 (en) 2002-02-28
MY132550A (en) 2007-10-31
HK1021372A1 (en) 2000-06-09
HUP0001165A2 (hu) 2000-11-28
DE69715886T2 (de) 2003-05-15
KR20000068325A (ko) 2000-11-25
NO990786D0 (no) 1999-02-19
AR009266A1 (es) 2000-04-12
KR100467402B1 (ko) 2005-01-24
PE107498A1 (es) 1999-01-28
DE69715886D1 (de) 2002-10-31
ID18059A (id) 1998-02-26
CA2264065A1 (en) 1998-02-26
SK22199A3 (en) 2000-02-14
CO4900047A1 (es) 2000-03-27
ES2184083T3 (es) 2003-04-01
CZ58199A3 (cs) 1999-06-16
JP2001503387A (ja) 2001-03-13
WO1998007694A1 (en) 1998-02-26
NO990786L (no) 1999-03-25
ATE224875T1 (de) 2002-10-15
SI0923550T1 (en) 2003-02-28
AU4299397A (en) 1998-03-06
RU2185375C2 (ru) 2002-07-20
TR199900363T2 (xx) 1999-04-21
NZ334736A (en) 2000-09-29
PL193731B1 (pl) 2007-03-30
CN1119328C (zh) 2003-08-27
IL128631A (en) 2002-09-12
TW438777B (en) 2001-06-07
SK283991B6 (sk) 2004-07-07
IL128631A0 (en) 2000-01-31
JP3654908B2 (ja) 2005-06-02
CN1233238A (zh) 1999-10-27
BR9711350A (pt) 1999-08-17
CZ294233B6 (cs) 2004-11-10
EP0923550B1 (en) 2002-09-25
CA2264065C (en) 2008-02-05
PL331740A1 (en) 1999-08-02
PT923550E (pt) 2003-01-31
HU226395B1 (en) 2008-11-28
DK0923550T3 (da) 2003-01-06

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