ZA972199B - Novel bridged cyclic amino acids as pharmaceutical agents. - Google Patents
Novel bridged cyclic amino acids as pharmaceutical agents.Info
- Publication number
- ZA972199B ZA972199B ZA9702199A ZA972199A ZA972199B ZA 972199 B ZA972199 B ZA 972199B ZA 9702199 A ZA9702199 A ZA 9702199A ZA 972199 A ZA972199 A ZA 972199A ZA 972199 B ZA972199 B ZA 972199B
- Authority
- ZA
- South Africa
- Prior art keywords
- amino acids
- pct
- cyclic amino
- pharmaceutical agents
- bridged cyclic
- Prior art date
Links
- -1 cyclic amino acids Chemical class 0.000 title abstract 2
- 239000008177 pharmaceutical agent Substances 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000035475 disorder Diseases 0.000 abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000006083 Hypokinesia Diseases 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 208000002173 dizziness Diseases 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 230000003483 hypokinetic effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 230000002981 neuropathic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/12—Antiepileptics; Anticonvulsants for grand-mal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
- C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
- C07C2602/46—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing nine carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1343396P | 1996-03-14 | 1996-03-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA972199B true ZA972199B (en) | 1997-09-17 |
Family
ID=21759944
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9702199A ZA972199B (en) | 1996-03-14 | 1997-03-13 | Novel bridged cyclic amino acids as pharmaceutical agents. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6020370A (xx) |
| EP (1) | EP0888285B1 (xx) |
| JP (1) | JP2000506862A (xx) |
| KR (1) | KR100487032B1 (xx) |
| AT (1) | ATE210629T1 (xx) |
| AU (1) | AU731279B2 (xx) |
| BR (1) | BR9708180A (xx) |
| CZ (1) | CZ287598A3 (xx) |
| DE (1) | DE69709070T2 (xx) |
| EA (1) | EA001214B1 (xx) |
| ES (1) | ES2169848T3 (xx) |
| IL (1) | IL125364A0 (xx) |
| NO (1) | NO984204D0 (xx) |
| NZ (1) | NZ331142A (xx) |
| PL (1) | PL185990B1 (xx) |
| SK (1) | SK282848B6 (xx) |
| WO (1) | WO1997033859A1 (xx) |
| ZA (1) | ZA972199B (xx) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU714980B2 (en) | 1996-07-24 | 2000-01-13 | Warner-Lambert Company Llc | Isobutylgaba and its derivatives for the treatment of pain |
| DE69814420T2 (de) * | 1997-09-18 | 2003-11-27 | Warner-Lambert Co. Llc, Morris Plains | Stereoselektive verfahren zur herstellung von gabapentinanalogen |
| DE19751062A1 (de) | 1997-11-18 | 1999-07-08 | Univ Ludwigs Albert | An 4-Stellung substituierte 2-Pyrrolidinon-Derivate zur Verringerung des extrazellulären Glutamat-Spiegels |
| US6984659B2 (en) | 1997-11-18 | 2006-01-10 | Klinikum Der Albert-Ludwigs Universitaet | 2-pyrrolidinone derivatives substituted at position 4 for reducing the extracellular glutamate level |
| PT1047678E (pt) * | 1997-12-16 | 2004-12-31 | Warner Lambert Co | Derivados do 1-aminometil-cicloalcano substituido em 1 (=analogos da gabapentina) sua preparacao e sua utilizacao no tratamento de disturbios neurologicos |
| NZ506793A (en) | 1998-05-26 | 2003-03-28 | Warner Lambert Co | Conformationally constrained amino acid compounds and their use for treating epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain and neuropathological disorders |
| JP2002520300A (ja) * | 1998-07-09 | 2002-07-09 | ワーナー−ランバート・カンパニー | Ｇａｂａ類縁体及び抗ウイルス剤を含んでなる帯状ヘルペスを治療するための医薬組成物 |
| NZ517044A (en) | 1999-07-22 | 2004-02-27 | Univ Rochester | Gamma-aminobutyric acid analogues, e.g. gabapentin and pregabalin, to treat symptoms of hormonal variation, including hot flushes, nausea, emesis and fever |
| AU2001247762A1 (en) * | 2000-03-28 | 2001-10-08 | Delorenzo, Robert, J | Inhibition of a novel calcium injury current that forms in neurons during injury prevents neuronal cell death |
| CN1279900C (zh) * | 2000-06-26 | 2006-10-18 | 沃尼尔·朗伯公司 | 用于睡眠障碍的加巴喷丁类似物 |
| US6900192B2 (en) * | 2000-10-06 | 2005-05-31 | Xenoport, Inc. | Bile-acid conjugates for providing sustained systemic concentrations of drugs |
| AU2002211863A1 (en) | 2000-10-06 | 2002-04-15 | Xenoport, Inc. | Bile-acid derived compounds for providing sustained systemic concentrations of drugs after oral administration |
| NZ528151A (en) * | 2001-04-19 | 2005-04-29 | Warner Lambert Co | Fused bicyclic or tricyclic amino acids |
| GB2374595A (en) * | 2001-04-19 | 2002-10-23 | Warner Lambert Co | Fused bicyclic or tricyclic amino acids |
| AU2002345638A1 (en) * | 2001-06-11 | 2002-12-23 | Xenoport, Inc. | Amino acid conjugates providing for sustained systemic concentrations of gaba analogues |
| US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US6818787B2 (en) * | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US8048917B2 (en) * | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| CN1533270A (zh) | 2001-06-11 | 2004-09-29 | ʲŵ��������˾ | 具有降低毒性的gaba类似物前药的口服给药剂型 |
| US7232924B2 (en) * | 2001-06-11 | 2007-06-19 | Xenoport, Inc. | Methods for synthesis of acyloxyalkyl derivatives of GABA analogs |
| WO2003077902A1 (en) | 2002-02-19 | 2003-09-25 | Xenoport, Inc. | Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof |
| WO2003080588A1 (en) | 2002-03-20 | 2003-10-02 | Xenoport | Cyclic 1-(acyloxy)-alkyl prodrugs of gaba analogs, compositions and uses thereof |
| CA2484891A1 (en) * | 2002-05-07 | 2003-11-20 | A & D Bioscience, Inc. | Conjugates comprising central nervous system active drug |
| US7183259B2 (en) * | 2002-05-17 | 2007-02-27 | Xenoport | Amino acid conjugates providing for sustained systemic concentrations of GABA analogues |
| US7060727B2 (en) | 2002-12-11 | 2006-06-13 | Xenoport, Inc. | Prodrugs of fused GABA analogs, pharmaceutical compositions and uses thereof |
| WO2004053192A1 (en) * | 2002-12-11 | 2004-06-24 | Xenoport, Inc. | Orally administered dosage forms of fused gaba analog prodrugs having reduced toxicity |
| CA2451267A1 (en) | 2002-12-13 | 2004-06-13 | Warner-Lambert Company Llc | Pharmaceutical uses for alpha2delta ligands |
| CA2679030A1 (en) | 2002-12-13 | 2004-07-01 | Warner-Lambert Company Llc | Alpha-2-delta ligand to treat lower urinary track symptoms |
| CA2520468A1 (en) * | 2003-03-31 | 2004-10-21 | Xenoport, Inc. | Treating or preventing hot flashes using prodrugs of gaba analogs |
| KR20060119971A (ko) | 2003-09-11 | 2006-11-24 | 제노포트 인코포레이티드 | Ｇａｂａ 유사체의 전구약물을 이용한 요실금의 치료및/또는 예방 |
| KR100828218B1 (ko) | 2003-09-12 | 2008-05-07 | 화이자 인코포레이티드 | 알파-2-델타 리간드 및 세로토닌/노르아드레날린 재흡수 억제제를 포함하는 조합물 |
| AU2004274002B2 (en) * | 2003-09-17 | 2011-04-28 | Arbor Pharmaceuticals, Llc | Treating or preventing restless legs syndrome using prodrugs of GABA analogs |
| DK1677767T3 (da) * | 2003-10-14 | 2011-10-24 | Xenoport Inc | Krystallinsk form af gamma-aminobutyrsyre-analog |
| ES2515092T3 (es) | 2003-12-11 | 2014-10-29 | Sunovion Pharmaceuticals Inc. | Combinación de un sedante y un modulador neurotransmisor y métodos de mejorar la calidad del sueño y de tratar la depresión |
| AU2005301970B2 (en) | 2004-11-04 | 2011-06-02 | Arbor Pharmaceuticals, Llc | Gabapentin prodrug sustained release oral dosage forms |
| AU2006325820B2 (en) * | 2005-12-12 | 2013-02-14 | Allaccem, Inc. | Methods and systems for preparing antimicrobial films and coatings |
| US7727978B2 (en) | 2006-08-24 | 2010-06-01 | Bristol-Myers Squibb Company | Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors |
| EP2101752A1 (en) * | 2006-12-08 | 2009-09-23 | Xenoport, Inc. | Use of prodrugs of gaba analogs for treating diseases |
| HRP20110634T1 (hr) | 2006-12-22 | 2011-10-31 | Recordati Ireland Limited | KOMBINIRANA TERAPIJA LIGANADA α<SUB>2</SUB>δ I NSAID ZA POREMEĆAJE DONJEG URINARNOG TRAKTA |
| AU2008218275B2 (en) | 2007-02-21 | 2013-06-20 | Allaccem, Incorporated | Bridged polycyclic compound based compositions for the inhibition and amelioration of disease |
| TW200908957A (en) * | 2007-06-15 | 2009-03-01 | Xenoport Inc | Use of prodrugs of GABA analogs, antispasticity agents, and prodrugs of GABAB receptor agonists for treating spasticity |
| US8188068B2 (en) * | 2007-08-10 | 2012-05-29 | Allaccem, Inc. | Bridged polycyclic compound based compositions for coating oral surfaces in pets |
| US8153618B2 (en) * | 2007-08-10 | 2012-04-10 | Allaccem, Inc. | Bridged polycyclic compound based compositions for topical applications for pets |
| US8153617B2 (en) * | 2007-08-10 | 2012-04-10 | Allaccem, Inc. | Bridged polycyclic compound based compositions for coating oral surfaces in humans |
| US8119658B2 (en) | 2007-10-01 | 2012-02-21 | Bristol-Myers Squibb Company | Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors |
| WO2009061934A1 (en) * | 2007-11-06 | 2009-05-14 | Xenoport, Inc. | Use of prodrugs of gaba b agonists for treating neuropathic and musculoskeletal pain |
| EP2250148B1 (en) | 2008-01-25 | 2016-08-17 | XenoPort, Inc. | Crystalline form of calcium-salts of (3s)-aminomethyl-5-methyl-hexanoic acids and methods of use |
| JP5291123B2 (ja) * | 2008-01-25 | 2013-09-18 | ゼノポート，インコーポレイティド | （３ｓ）−アミノメチル−５−ヘキサン酸プロドラッグの結晶形態及びその使用 |
| US7868043B2 (en) | 2008-01-25 | 2011-01-11 | Xenoport, Inc. | Mesophasic forms of (3S)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use |
| CA2732984A1 (en) * | 2008-08-07 | 2010-02-11 | Kyorin Pharmaceutical Co., Ltd. | Process for production of bicyclo[2.2.2]octylamine derivative |
| CN102216257B (zh) | 2008-10-08 | 2015-11-25 | 凯飞药业公司 | Gaba偶联物及其使用方法 |
| WO2010084798A1 (ja) * | 2009-01-21 | 2010-07-29 | 第一三共株式会社 | ３環性化合物 |
| US20110130454A1 (en) * | 2009-11-24 | 2011-06-02 | Xenoport, Inc. | Prodrugs of gamma-amino acid, alpha-2-delta ligands, pharmaceutical compositions and uses thereof |
| US20110124705A1 (en) * | 2009-11-24 | 2011-05-26 | Xenoport, Inc. | Prodrugs of alpha-2-delta ligands, pharmaceutical compositions and uses thereof |
| US9066853B2 (en) | 2013-01-15 | 2015-06-30 | Warsaw Orthopedic, Inc. | Clonidine compounds in a biodegradable fiber |
| HUE047629T2 (hu) | 2013-01-28 | 2020-05-28 | Lopez Hector L | Eljárások ß-alanin tolerancia, farmakodinamika és hatékonyság javítására és azok alkalmazása |
| EP4227293A3 (en) | 2018-05-14 | 2023-10-04 | Xgene Pharmaceutical Inc | Crystalline forms of 1-(acyloxy)-alkyl carbamate drug conjugates of naproxen and pregabalin |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3743742A (en) * | 1969-06-17 | 1973-07-03 | Merck & Co Inc | Producing anti-fibrinolytic activity with aminobicycloacetic acid derivatives |
| US3641129A (en) * | 1969-06-17 | 1972-02-08 | Merck & Co Inc | Antifibrinolytic compounds |
| YU36150B (en) * | 1974-11-22 | 1982-02-25 | Pliva Zagreb | Process for preparing alpha-amino-1-adamantyl acetic acid |
| US4087544A (en) * | 1974-12-21 | 1978-05-02 | Warner-Lambert Company | Treatment of cranial dysfunctions using novel cyclic amino acids |
| DE2460891C2 (de) * | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| DE2543821C2 (de) * | 1974-12-21 | 1984-10-18 | Gödecke AG, 1000 Berlin | Bestimmte Salze und Ester von 1-Aminomethyl-1-cycloalkanessigsäuren und diese Verbindungen enthaltende Arzneimittel |
-
1997
- 1997-02-18 SK SK1248-98A patent/SK282848B6/sk unknown
- 1997-02-18 PL PL97328800A patent/PL185990B1/pl not_active IP Right Cessation
- 1997-02-18 AU AU21271/97A patent/AU731279B2/en not_active Ceased
- 1997-02-18 AT AT97906630T patent/ATE210629T1/de not_active IP Right Cessation
- 1997-02-18 JP JP9532604A patent/JP2000506862A/ja not_active Ceased
- 1997-02-18 EA EA199800797A patent/EA001214B1/ru unknown
- 1997-02-18 BR BR9708180A patent/BR9708180A/pt not_active IP Right Cessation
- 1997-02-18 IL IL12536497A patent/IL125364A0/xx not_active IP Right Cessation
- 1997-02-18 DE DE69709070T patent/DE69709070T2/de not_active Expired - Fee Related
- 1997-02-18 KR KR10-1998-0707228A patent/KR100487032B1/ko not_active Expired - Fee Related
- 1997-02-18 WO PCT/US1997/002401 patent/WO1997033859A1/en not_active Application Discontinuation
- 1997-02-18 US US09/068,861 patent/US6020370A/en not_active Expired - Fee Related
- 1997-02-18 NZ NZ331142A patent/NZ331142A/en unknown
- 1997-02-18 CZ CZ982875A patent/CZ287598A3/cs unknown
- 1997-02-18 ES ES97906630T patent/ES2169848T3/es not_active Expired - Lifetime
- 1997-02-18 EP EP97906630A patent/EP0888285B1/en not_active Expired - Lifetime
- 1997-03-13 ZA ZA9702199A patent/ZA972199B/xx unknown
-
1998
- 1998-09-11 NO NO984204A patent/NO984204D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ331142A (en) | 2001-04-27 |
| KR19990087755A (ko) | 1999-12-27 |
| IL125364A0 (en) | 1999-03-12 |
| EA001214B1 (ru) | 2000-12-25 |
| EP0888285B1 (en) | 2001-12-12 |
| EP0888285A1 (en) | 1999-01-07 |
| JP2000506862A (ja) | 2000-06-06 |
| PL185990B1 (pl) | 2003-09-30 |
| NO984204L (no) | 1998-09-11 |
| US6020370A (en) | 2000-02-01 |
| ES2169848T3 (es) | 2002-07-16 |
| DE69709070T2 (de) | 2002-06-20 |
| ATE210629T1 (de) | 2001-12-15 |
| KR100487032B1 (ko) | 2005-12-21 |
| BR9708180A (pt) | 1999-07-27 |
| AU731279B2 (en) | 2001-03-29 |
| CZ287598A3 (cs) | 1999-02-17 |
| SK124898A3 (en) | 1999-02-11 |
| NO984204D0 (no) | 1998-09-11 |
| SK282848B6 (sk) | 2002-12-03 |
| DE69709070D1 (de) | 2002-01-24 |
| EA199800797A1 (ru) | 1999-04-29 |
| AU2127197A (en) | 1997-10-01 |
| PL328800A1 (en) | 1999-02-15 |
| WO1997033859A1 (en) | 1997-09-18 |
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