[go: up one dir, main page]

ZA965019B - Isothermal PCR. - Google Patents

Isothermal PCR.

Info

Publication number
ZA965019B
ZA965019B ZA9605019A ZA965019A ZA965019B ZA 965019 B ZA965019 B ZA 965019B ZA 9605019 A ZA9605019 A ZA 9605019A ZA 965019 A ZA965019 A ZA 965019A ZA 965019 B ZA965019 B ZA 965019B
Authority
ZA
South Africa
Prior art keywords
isothermal pcr
isothermal
pcr
Prior art date
Application number
ZA9605019A
Inventor
Gottfried Himmler
Thomas Schlederer
Original Assignee
Gottfried Himmler
Thomas Schlederer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gottfried Himmler, Thomas Schlederer filed Critical Gottfried Himmler
Publication of ZA965019B publication Critical patent/ZA965019B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6862—Ligase chain reaction [LCR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
ZA9605019A 1995-06-13 1996-06-13 Isothermal PCR. ZA965019B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0100795A AT402203B (en) 1995-06-13 1995-06-13 METHOD FOR TRANSCRIPTION-FREE AMPLIFICATION OF NUCLEIC ACIDS

Publications (1)

Publication Number Publication Date
ZA965019B true ZA965019B (en) 1997-02-24

Family

ID=3504789

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9605019A ZA965019B (en) 1995-06-13 1996-06-13 Isothermal PCR.

Country Status (10)

Country Link
US (1) US6033881A (en)
EP (1) EP0833942B1 (en)
JP (1) JPH11509406A (en)
AR (1) AR002470A1 (en)
AT (2) AT402203B (en)
AU (1) AU5887296A (en)
CO (1) CO4480062A1 (en)
DE (1) DE59605824D1 (en)
WO (1) WO1997000330A2 (en)
ZA (1) ZA965019B (en)

Families Citing this family (138)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6261808B1 (en) * 1992-08-04 2001-07-17 Replicon, Inc. Amplification of nucleic acid molecules via circular replicons
WO1994003624A1 (en) * 1992-08-04 1994-02-17 Auerbach Jeffrey I Methods for the isothermal amplification of nucleic acid molecules
FR2708288B1 (en) 1993-07-26 1995-09-01 Bio Merieux Method for amplification of nucleic acids by transcription using displacement, reagents and necessary for the implementation of this method.
US5854033A (en) * 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
DE69612013T2 (en) * 1995-11-21 2001-08-02 Yale University, New Haven UNIMOLECULAR SEGMENT AMPLIFICATION AND DETERMINATION
ATE364718T1 (en) 1997-04-01 2007-07-15 Solexa Ltd METHOD FOR DUPLICATION OF NUCLEIC ACID
US6743605B1 (en) 1998-06-24 2004-06-01 Enzo Life Sciences, Inc. Linear amplification of specific nucleic acid sequences
US8445664B2 (en) 1998-06-24 2013-05-21 Enzo Diagnostics, Inc. Kits for amplifying and detecting nucleic acid sequences
DE69937223T3 (en) 1998-11-09 2011-05-05 Eiken Kagaku K.K. PROCESS FOR SYNTHESIS OF NUCLEIC ACIDS
JP4721603B2 (en) * 1999-11-08 2011-07-13 栄研化学株式会社 Mutation and / or polymorphism detection method
CN1415020A (en) 1999-11-08 2003-04-30 荣研化学株式会社 Method of detecting variation and/or polymorphism
US7205129B1 (en) 2000-02-28 2007-04-17 Qiagen Gmbh Method for reducing artifacts in nucleic acid amplification
WO2001077317A1 (en) * 2000-04-07 2001-10-18 Eiken Kagaku Kabushiki Kaisha Method of amplifying nucleic acid by using double-stranded nucleic acid as template
US20060166227A1 (en) * 2000-06-20 2006-07-27 Stephen Kingsmore Protein expression profiling
US6531283B1 (en) 2000-06-20 2003-03-11 Molecular Staging, Inc. Protein expression profiling
US6323009B1 (en) * 2000-06-28 2001-11-27 Molecular Staging, Inc. Multiply-primed amplification of nucleic acid sequences
AU2001271722B2 (en) 2000-06-30 2006-04-13 Qiagen, Gmbh Signal amplification with lollipop probes
US6861222B2 (en) 2000-11-09 2005-03-01 Yale University Nucleic acid detection using structured probes
AR031640A1 (en) * 2000-12-08 2003-09-24 Applied Research Systems ISOTHERMAL AMPLIFICATION OF NUCLEIC ACIDS IN A SOLID SUPPORT
US6573051B2 (en) * 2001-03-09 2003-06-03 Molecular Staging, Inc. Open circle probes with intramolecular stem structures
ATE397095T1 (en) 2001-04-20 2008-06-15 Penn State Res Found METHOD FOR MANIPULATION OF NUCLEIC ACIDS
US6977148B2 (en) * 2001-10-15 2005-12-20 Qiagen Gmbh Multiple displacement amplification
US7297485B2 (en) * 2001-10-15 2007-11-20 Qiagen Gmbh Method for nucleic acid amplification that results in low amplification bias
US6617137B2 (en) * 2001-10-15 2003-09-09 Molecular Staging Inc. Method of amplifying whole genomes without subjecting the genome to denaturing conditions
US7553619B2 (en) * 2002-02-08 2009-06-30 Qiagen Gmbh Detection method using dissociated rolling circle amplification
JP4377810B2 (en) 2002-05-17 2009-12-02 アメリカ合衆国 Molecular identification of Aspergillus species
JP2006516883A (en) 2002-09-19 2006-07-13 アメリカ合衆国 P. Arashi polypeptide, Capsicum fly polypeptide, and method of use
US7485306B2 (en) 2002-10-29 2009-02-03 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Lutzomyia longipalpis polypeptides and methods of use
TW200413527A (en) 2002-10-29 2004-08-01 Riken Amplification of nucleic acid
US20040121338A1 (en) * 2002-12-19 2004-06-24 Alsmadi Osama A. Real-time detection of rolling circle amplification products
EP1583843B1 (en) * 2002-12-20 2018-07-18 QIAGEN GmbH Single primer whole genome amplification
US7955795B2 (en) * 2003-06-06 2011-06-07 Qiagen Gmbh Method of whole genome amplification with reduced artifact production
US9487823B2 (en) * 2002-12-20 2016-11-08 Qiagen Gmbh Nucleic acid amplification
US8043834B2 (en) * 2003-03-31 2011-10-25 Qiagen Gmbh Universal reagents for rolling circle amplification and methods of use
US20040248103A1 (en) * 2003-06-04 2004-12-09 Feaver William John Proximity-mediated rolling circle amplification
US8206902B2 (en) 2003-12-25 2012-06-26 Riken Method of amplifying nucleic acid and method of detecting mutated nucleic acid using the same
EP1863908B1 (en) * 2005-04-01 2010-11-17 Qiagen GmbH Reverse transcription and amplification of rna with simultaneous degradation of dna
EP1929045B9 (en) * 2005-09-06 2012-06-20 Gen-Probe Incorporated Methods, compositions and kits for isothermal amplification of nucleic acids
EP1762627A1 (en) * 2005-09-09 2007-03-14 Qiagen GmbH Method for the activation of a nucleic acid for performing a polymerase reaction
AU2006304268B2 (en) 2005-10-14 2011-09-29 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Rabies virus vector systems and compositions and methods thereof
GB0522310D0 (en) 2005-11-01 2005-12-07 Solexa Ltd Methods of preparing libraries of template polynucleotides
GB0524069D0 (en) * 2005-11-25 2006-01-04 Solexa Ltd Preparation of templates for solid phase amplification
US20080057499A1 (en) * 2006-02-06 2008-03-06 Affymetrix, Inc. Methods for high specificity whole genome amplification and hybridization
EP2428801B1 (en) 2006-03-14 2014-05-07 Oregon Health and Science University Methods for detecting a mycobacterium tuberculosis infection
EP2021503A1 (en) * 2006-03-17 2009-02-11 Solexa Ltd. Isothermal methods for creating clonal single molecule arrays
DE102006020885A1 (en) * 2006-05-05 2007-11-08 Qiagen Gmbh Inserting a tag sequence into a nucleic acid comprises using an anchor oligonucleotide comprising a hybridizing anchor sequence and a nonhybridizing tag-template sequence
US7501254B2 (en) * 2006-07-20 2009-03-10 Ghc Technologies, Inc. Methods and compositions for amplification and capture of nucleic acid sequences
CN103536915A (en) 2006-12-27 2014-01-29 埃默里大学 Compositions and methods for the treatment of infections and tumors
WO2008093098A2 (en) 2007-02-02 2008-08-07 Illumina Cambridge Limited Methods for indexing samples and sequencing multiple nucleotide templates
JP5596980B2 (en) 2007-02-28 2014-10-01 アメリカ合衆国 Brachyury polypeptides and methods of use
US7838235B2 (en) * 2007-03-28 2010-11-23 Signal Diagnostics System and method for high resolution analysis of nucleic acids to detect sequence variations
US9689031B2 (en) 2007-07-14 2017-06-27 Ionian Technologies, Inc. Nicking and extension amplification reaction for the exponential amplification of nucleic acids
JP2009284896A (en) 2007-07-26 2009-12-10 Fujifilm Corp Nucleic acid amplification method
DE602008004702D1 (en) * 2007-08-15 2011-03-10 Fujifilm Corp Process for the amplification of nucleic acid
JP2009048280A (en) * 2007-08-15 2009-03-05 Nikon Corp Mechanism analysis program
EP2058406A3 (en) 2007-11-06 2009-10-28 Fujifilm Corporation RNA detection method
US8420323B2 (en) * 2007-11-14 2013-04-16 Fujifilm Corporation Nucleic acid amplification method
CN102089443A (en) 2008-04-10 2011-06-08 基因信息公司 Method and apparatus for determining a probability of colorectal cancer in a subject
EP2353008A2 (en) 2008-09-22 2011-08-10 Oregon Health and Science University Methods for detecting a mycobacterium tuberculosis infection
US10669574B2 (en) 2008-11-18 2020-06-02 XCR Diagnostics, Inc. DNA amplification technology
CA2744449C (en) 2008-11-28 2019-01-29 Emory University Methods for the treatment of infections and tumors
JP5616584B2 (en) 2009-01-09 2014-10-29 富士フイルム株式会社 Nucleic acid sequence replication method
JP2010161935A (en) 2009-01-13 2010-07-29 Fujifilm Corp Method for reducing dispersion in nucleic acid amplification reaction
US20120004133A1 (en) 2009-02-20 2012-01-05 The Johns Hopkins University Method for the diagnosis of age-associated vascular disorders
US9309557B2 (en) 2010-12-17 2016-04-12 Life Technologies Corporation Nucleic acid amplification
US9334531B2 (en) 2010-12-17 2016-05-10 Life Technologies Corporation Nucleic acid amplification
US9309566B2 (en) 2010-12-17 2016-04-12 Life Technologies Corporation Methods, compositions, systems, apparatuses and kits for nucleic acid amplification
AU2010253978B2 (en) 2009-05-29 2014-12-11 Ventana Medical Systems, Inc. Methods of scoring gene copy number in a biological sample using in situ hybridization
WO2010138908A1 (en) 2009-05-29 2010-12-02 Ventana Medical Systems, Inc. Igfir gene copy number as a prognostic marker in a non-small cell lung cancer
CA2774636C (en) 2009-09-25 2019-05-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Neutralizing antibodies to hiv-1 and their use
WO2011047340A1 (en) 2009-10-16 2011-04-21 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Insertion of foreign genes in rubella virus and their stable expression in a live, attenuated viral vaccine
WO2011063263A2 (en) 2009-11-20 2011-05-26 Oregon Health & Science University Methods for producing an immune response to tuberculosis
WO2011133474A2 (en) 2010-04-18 2011-10-27 Beth Israel Deaconess Medical Center Methods of predicting predisposition to or risk of kidney disease
EP2558596B1 (en) 2010-04-16 2018-03-14 The Government Of The United States Of America As Reresented By The Secretary Of The Department Of Health & Human Services Real time pcr assay for detection of bacterial respiratory pathogens
ES2695899T3 (en) 2010-06-16 2019-01-11 Univ Pittsburgh Commonwealth Sys Higher Education Antibodies against endoplasmin and its use
BR112013004691A2 (en) 2010-08-30 2017-11-21 Dow Agrosciences Llc marked gene activation DNA construct, marked population of maize plants, method for generating it and method for generating a marked maize plant
BR112013004948B8 (en) 2010-08-30 2022-10-11 Dow Agrosciences Llc CHIMERIC TRANSCRIPTION REGULATORY REGION INCLUDING SUGARCANE BACILLIFORM VIRAL ENHANCER (SCBV), CONSTRUCTION AND PRODUCTION PROCESS OF A TRANSGENIC PLANT
CN118086471A (en) 2010-12-17 2024-05-28 生命技术公司 Methods, compositions, systems, instruments and kits for nucleic acid amplification
MX2013008367A (en) 2011-01-25 2013-08-12 Almac Diagnostics Ltd Colon cancer gene expression signatures and methods of use.
US9150644B2 (en) 2011-04-12 2015-10-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II
WO2013006684A1 (en) 2011-07-05 2013-01-10 The Gov. Of The U.S.A. As Represented By The Secretary Of The Dept. Of Health And Human Services. Hiv-1 genotyping assay for global surveillance of hiv-1 drug resistance
US9352312B2 (en) 2011-09-23 2016-05-31 Alere Switzerland Gmbh System and apparatus for reactions
WO2013049535A2 (en) 2011-09-30 2013-04-04 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Influenza vaccine
DK2780466T3 (en) 2011-11-15 2019-05-13 Univ Bruxelles DETECTION OF STREPTOCOCUS PNEUMONIAE IN BLOOD
EP2820136B1 (en) 2012-02-29 2018-03-28 Dow AgroSciences LLC Sugarcane bacilliform viral (scbv) enhancer and its use in plant functional genomics
US9421250B2 (en) 2012-03-23 2016-08-23 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Pathogenic phlebovirus isolates and compositions and methods of use
US9428813B2 (en) 2012-03-26 2016-08-30 The United States Of America, As Represented By The Secretary, Dept. Of Health & Human Services DNA methylation analysis for the diagnosis, prognosis and treatment of adrenal neoplasms
WO2013152352A1 (en) 2012-04-06 2013-10-10 The United States Of America, As Represented By The Secretary, Department Of Health And Human Servic Live, attenuated rubella vector to express vaccine antigens
UA116205C2 (en) 2012-04-09 2018-02-26 Енвіролоджикс Інк. Compositions and methods for quantifying a nucleic acid sequence in a sample
CA2871490C (en) 2012-04-27 2022-10-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Use of cpg oligonucleotides co-formulated with an antibiotic to accelerate wound healing
US9803251B2 (en) 2012-05-03 2017-10-31 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Methods of detecting influenza virus
US9394574B2 (en) 2012-06-12 2016-07-19 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Methods for detecting Legionella nucleic acids in a sample
WO2013192100A1 (en) 2012-06-18 2013-12-27 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods and compositions for detecting jc virus
ES2752190T3 (en) 2012-09-14 2020-04-03 Us Health Brachyury protein, adenoviral vectors encoding Brachyury protein and their use
US9775895B2 (en) 2012-12-12 2017-10-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services HIV therapeutics and methods of making and using same
EP3323884A1 (en) 2013-02-01 2018-05-23 The United States Of America as Represented by the Secretary, Department of Health an Human Service Method for generating retinal pigment epithelium (rpe) cells from induced pluripotent stem cells (ipscs)
EP2956169B1 (en) 2013-02-12 2018-04-11 THE UNITED STATES OF AMERICA, represented by the S Monoclonal antibodies that neutralize norovirus
US10612088B2 (en) 2013-03-14 2020-04-07 The Broad Institute, Inc. Massively multiplexed RNA sequencing
AU2014233152A1 (en) 2013-03-15 2015-09-17 Theranos Ip Company, Llc Nucleic acid amplification
JP2016521120A (en) 2013-03-15 2016-07-21 セラノス， インコーポレイテッド Nucleic acid amplification
US10450595B2 (en) 2013-03-15 2019-10-22 Theranos Ip Company, Llc Nucleic acid amplification
EP3587592A1 (en) 2013-03-15 2020-01-01 Theranos IP Company, LLC Nucleic acid amplification
CA2909721A1 (en) 2013-04-19 2014-10-23 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Lone star virus
WO2014183052A1 (en) 2013-05-09 2014-11-13 The United States Of America, As Represented By The Secretary, Depart Of Health And Human Services Single-domain vhh antibodies directed to norovirus gi.1 and gii.4 and their use
WO2015035260A1 (en) 2013-09-06 2015-03-12 Theranos, Inc. Systems and methods for detecting infectious diseases
KR102323375B1 (en) 2013-10-09 2021-11-08 플루어레센트릭 인코포레이티드 Multiplex Probes
WO2015061475A2 (en) 2013-10-22 2015-04-30 THE GOVERNMENT OF THE USA as represented by THE SECRETARY OF THE DEPARTMENT OF HEATLH AND HUMAN SERV Compositions and methods for detection and discrimination of influenza viruses
US10398772B2 (en) 2014-01-08 2019-09-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Ras pathways as markers of protection against HIV and methods to improve vaccine efficacy
EP3107930A1 (en) 2014-02-21 2016-12-28 THE UNITED STATES OF AMERICA, represented by the S Hiv-2 nucleic acids and methods of detection
US20170044631A1 (en) 2014-04-14 2017-02-16 The Unite States of America, as represented by the Secretary, Dept. of Health and Human Services Methods for rapid detection and identification of viral nucleic acids
WO2015199976A1 (en) 2014-06-24 2015-12-30 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Target activated microdissection
EP3175244A4 (en) 2014-07-30 2018-06-13 Mor Research Applications Ltd. Compositions for treatment of acute lymphoblastic leukemia and methods of use thereof
EP3177320B1 (en) 2014-07-31 2021-01-06 The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services Human monoclonal antibodies against epha4 and their use
WO2016089920A1 (en) 2014-12-01 2016-06-09 The Broad Institute, Inc. Method for in situ determination of nucleic acid proximity
WO2016090170A1 (en) 2014-12-05 2016-06-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services A potent anti-influenza a neuraminidase subtype n1 antibody
WO2016134144A1 (en) 2015-02-20 2016-08-25 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods and reagents for detecting ebola virus
CN107614700A (en) 2015-03-11 2018-01-19 布罗德研究所有限公司 genotype and phenotype coupling
EP3359651A1 (en) 2015-10-05 2018-08-15 THE UNITED STATES OF AMERICA, represented by the S Human rota virus g9p[6]strain and use as a vaccine
WO2017192589A1 (en) 2016-05-02 2017-11-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Neutralizing antibodies to influenza ha and their use and identification
US11155885B2 (en) 2016-05-20 2021-10-26 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Real-time reverse transcriptase-polymerase chain reaction assay with modified probe for the diagnosis of rabies viruses and other lyssaviruses
WO2018005284A1 (en) 2016-06-27 2018-01-04 The United State Of America, As Represented By The Secretary, Department Of Health And Human Services Methods and compositions for influenza a virus subtyping
US12209292B2 (en) 2016-08-26 2025-01-28 The Broad Institute, Inc. Nucleic acid amplification assays for detection of pathogens
US11447530B2 (en) 2016-12-06 2022-09-20 Oregon State University Compositions and methods for enhanced production of enduracidin in a genetically engineered strain of streptomyces fungicidicus
US11708613B2 (en) 2017-05-03 2023-07-25 The United States of America, as Represened by the Secretary, Department of Health and Human Services Rapid detection of Zika virus by reverse transcription loop-mediated isothermal amplification
WO2018232028A1 (en) 2017-06-14 2018-12-20 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Detection of blaimp antibacterial resistance genes
GB201710838D0 (en) 2017-07-05 2017-08-16 Ucl Business Plc Bispecific antibodies
AU2018335575B2 (en) 2017-09-25 2024-07-04 Fred Hutchinson Cancer Center High efficiency targeted in situ genome-wide profiling
EP3692152A4 (en) 2017-10-04 2021-12-01 The Broad Institute, Inc. PROCEDURES AND COMPOSITIONS FOR MODIFYING THE FUNCTION AND STRUCTURE OF CHROMATINE BANDS AND / OR DOMAINS
WO2019133727A1 (en) 2017-12-29 2019-07-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Universal influenza virus probe set for enrichment of any influenza virus nucleic acid
WO2019152860A1 (en) 2018-02-02 2019-08-08 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Random amplification methods for extremely low input nucleic acids
CA3107590A1 (en) 2018-07-27 2020-01-30 Aperta Biosciences, Llc Spinosyn formulations for treatment of demodex-induced ocular and facial conditions
WO2020123787A1 (en) 2018-12-12 2020-06-18 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Integrated proviral sequencing assay
WO2020210754A1 (en) 2019-04-10 2020-10-15 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Computational filtering of methylated sequence data for predictive modeling
US20220214332A1 (en) 2019-05-30 2022-07-07 Oregon Health & Science University Methods for Detecting A Mycobacterium Tuberculosis Infection
BR112022001265A8 (en) 2019-07-23 2022-10-18 Snapdna SYSTEM AND METHOD TO DETECT AND MONITOR PATHOGENS
US11844800B2 (en) 2019-10-30 2023-12-19 Massachusetts Institute Of Technology Methods and compositions for predicting and preventing relapse of acute lymphoblastic leukemia
WO2022056078A1 (en) 2020-09-11 2022-03-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Rnase h-assisted detection assay for rna (radar)
WO2024191684A1 (en) 2023-03-10 2024-09-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Detection of hepatitis c virus ribonucleic acid from whole blood using reverse transcription loop-mediated isothermal amplification

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5322770A (en) * 1989-12-22 1994-06-21 Hoffman-Laroche Inc. Reverse transcription with thermostable DNA polymerases - high temperature reverse transcription
WO1990001069A1 (en) * 1988-07-20 1990-02-08 Segev Diagnostics, Inc. Process for amplifying and detecting nucleic acid sequences
WO1990010064A1 (en) * 1989-03-03 1990-09-07 Genentech, Inc. Improved methods for in vitro dna amplification and genomic cloning and mapping
US5273881A (en) * 1990-05-07 1993-12-28 Daikin Industries, Ltd. Diagnostic applications of double D-loop formation
US5527670A (en) * 1990-09-12 1996-06-18 Scientific Generics Limited Electrochemical denaturation of double-stranded nucleic acid
US5455166A (en) * 1991-01-31 1995-10-03 Becton, Dickinson And Company Strand displacement amplification
ES2091976T3 (en) 1991-06-20 1996-11-16 Hoffmann La Roche PERFECTED METHODS FOR THE AMPLIFICATION OF NUCLEIC ACID.
BR9206985A (en) * 1991-12-24 1995-12-05 Tepnel Medical Ltd Processes for manipulating a nucleic acid sequence to test a sample for the presence of a marker nucleic acid in the same flow passage vessel solid support apparatus and process for producing the same
WO1994003635A1 (en) * 1992-08-04 1994-02-17 Institute Of Molecular Biology & Biotechnology Rapid amplification and detection of nucleic acids
US5340728A (en) 1992-12-09 1994-08-23 E. I. Du Pont De Nemours And Company Method for amplification of targeted segments of nucleic acid using nested polymerase chain reaction
WO1995025180A1 (en) * 1994-03-16 1995-09-21 Gen-Probe Incorporated Isothermal strand displacement nucleic acid amplification

Also Published As

Publication number Publication date
US6033881A (en) 2000-03-07
AT402203B (en) 1997-03-25
ATA100795A (en) 1996-07-15
WO1997000330A2 (en) 1997-01-03
AU5887296A (en) 1997-01-15
DE59605824D1 (en) 2000-10-05
CO4480062A1 (en) 1997-07-09
JPH11509406A (en) 1999-08-24
EP0833942B1 (en) 2000-08-30
WO1997000330A3 (en) 1997-04-10
ATE195976T1 (en) 2000-09-15
EP0833942A2 (en) 1998-04-08
AR002470A1 (en) 1998-03-25

Similar Documents

Publication Publication Date Title
ZA965019B (en) Isothermal PCR.
ZA967315B (en) Biphenylamides.
ZA964136B (en) Catalytic DNA.
ZA9710429B (en) Broad-spectrumδ-endotoxins.
MX213417B (en) Phenylpyridazinones.
HK1016976A1 (en) Resorcinyl-triazine.
ZA964468B (en) Triazolylmethyl-cyclopentanols.
ZA961955B (en) Indazolecarboxamides.
ZA971272B (en) Gene expression.
DE69610844D1 (en) Hydroformylierungsverfahren.
ZA975742B (en) Modified oligonucleotides.
ZA98387B (en) Novel microorganisms.
ZA961082B (en) DNA sequence.
ZA966399B (en) Endothelin-receptor-antagonists.
ZA97928B (en) Novel heteroaryl-oxazolidinones.
HK1017834A1 (en) Bodyshaper.
ZA97572B (en) 1-pyrazol-3-ylethyl-4-indol-3-ylpiperidines.
ZA967545B (en) Pharmaceuticals.
ZA964565B (en) Pyridiniminyl-1,2-benzisoxazoles and -benzisothiazoles
ZA983705B (en) Pregnan-3-ol-20-ones.
ZA97310B (en) Pharmaceuticals.
ZA966933B (en) Endothelin-receptor-antagonists.
ZA966750B (en) Halogenobenzimidazoles.
ZA971466B (en) Endothelin-receptor-antagonists.
ZA967314B (en) Carbamoylcarboxamides.