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ZA934868B - Amidines derived from 3-aminoethyl indoles and process for the preparation thereof - Google Patents

Amidines derived from 3-aminoethyl indoles and process for the preparation thereof

Info

Publication number
ZA934868B
ZA934868B ZA934868A ZA934868A ZA934868B ZA 934868 B ZA934868 B ZA 934868B ZA 934868 A ZA934868 A ZA 934868A ZA 934868 A ZA934868 A ZA 934868A ZA 934868 B ZA934868 B ZA 934868B
Authority
ZA
South Africa
Prior art keywords
preparation
indoles
aminoethyl
amidines derived
amidines
Prior art date
Application number
ZA934868A
Other languages
English (en)
Inventor
Jose Ma Caldero Ges
Anna Bosch Rovira
Joan Roca Acin
Pere Dalmases Barjoan
Francisco Marquillas Olondriz
Original Assignee
Vita Invest Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vita Invest Sa filed Critical Vita Invest Sa
Publication of ZA934868B publication Critical patent/ZA934868B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA934868A 1992-07-20 1993-07-07 Amidines derived from 3-aminoethyl indoles and process for the preparation thereof ZA934868B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09201513A ES2055651B1 (es) 1992-07-20 1992-07-20 Procedimiento para la obtencion de nuevas amidinas derivadas de 3-aminoetilindoles.

Publications (1)

Publication Number Publication Date
ZA934868B true ZA934868B (en) 1994-02-04

Family

ID=8277714

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA934868A ZA934868B (en) 1992-07-20 1993-07-07 Amidines derived from 3-aminoethyl indoles and process for the preparation thereof

Country Status (11)

Country Link
US (1) US5331005A (fi)
EP (1) EP0580539A3 (fi)
JP (1) JPH06179651A (fi)
KR (1) KR940005475A (fi)
AU (1) AU4164393A (fi)
CA (1) CA2100034A1 (fi)
ES (1) ES2055651B1 (fi)
FI (1) FI933276A (fi)
HU (1) HUT70183A (fi)
NO (1) NO932375L (fi)
ZA (1) ZA934868B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
KR20020080732A (ko) * 2001-04-17 2002-10-26 김연욱 연수기
KR100496125B1 (ko) * 2002-12-13 2005-06-16 신희승 누수 감시 시스템
ATE489138T1 (de) 2005-04-13 2010-12-15 Neuraxon Inc Substituierte indolverbindungen mit nos-hemmender aktivität
CA2643822A1 (en) * 2006-04-13 2007-10-25 Neuraxon, Inc 1,5 and 3,6- substituted indole compounds having nos inhibitory activity
KR20100103799A (ko) * 2007-11-16 2010-09-28 네우렉슨 인코포레이티드 내장통을 치료하기 위한 인돌 화합물 및 방법
CA2705422A1 (en) * 2007-11-16 2009-05-22 The Arizona Board Of Regents On Behalf Of The University Of Arizona Methods for treating visceral pain
CA2705833A1 (en) * 2007-11-16 2009-05-22 Subhash C. Annedi 3,5-substituted indole compounds having nos and norepinephrine reuptake inhibitory activity

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI753673A (fi) * 1975-01-15 1976-07-16 Merck & Co Inc
IT1170387B (it) * 1982-06-07 1987-06-03 Glaxo Group Ltd Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono
HU196752B (en) * 1983-12-06 1989-01-30 Glaxo Group Ltd Process for production of medical compositions containing indole-derivatives and these compounds
GB8332434D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Production of chemical compounds
GB8419575D0 (en) * 1984-08-01 1984-09-05 Glaxo Group Ltd Chemical compounds
GB2162522B (en) * 1984-08-01 1988-02-24 Glaxo Group Ltd An indole derivative

Also Published As

Publication number Publication date
HUT70183A (en) 1995-09-28
FI933276A0 (fi) 1993-07-20
ES2055651A1 (es) 1994-08-16
NO932375L (no) 1994-01-21
KR940005475A (ko) 1994-03-21
FI933276A (fi) 1994-01-21
EP0580539A3 (en) 1994-05-18
AU4164393A (en) 1994-01-27
ES2055651B1 (es) 1995-03-01
CA2100034A1 (en) 1994-01-21
NO932375D0 (no) 1993-06-29
JPH06179651A (ja) 1994-06-28
EP0580539A2 (en) 1994-01-26
US5331005A (en) 1994-07-19
HU9302078D0 (en) 1993-10-28

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