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ZA927501B - Imidazolyl-propenoic acid derivatives. - Google Patents

Imidazolyl-propenoic acid derivatives.

Info

Publication number
ZA927501B
ZA927501B ZA927501A ZA927501A ZA927501B ZA 927501 B ZA927501 B ZA 927501B ZA 927501 A ZA927501 A ZA 927501A ZA 927501 A ZA927501 A ZA 927501A ZA 927501 B ZA927501 B ZA 927501B
Authority
ZA
South Africa
Prior art keywords
imidazolyl
acid derivatives
propenoic acid
propenoic
derivatives
Prior art date
Application number
ZA927501A
Other languages
English (en)
Inventor
Thomas Kraemer
Juergen Dressel
Rudolf Hanko
Walter Huebsch
Ulrich Mueller
Matthias Mueller-Gliemann
Martin Beuck
Stanislav Kazda
Johannes-Peter Stasch
Andreas Knorr
Stefan Wohlfeil
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA927501B publication Critical patent/ZA927501B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA927501A 1991-10-01 1992-09-30 Imidazolyl-propenoic acid derivatives. ZA927501B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4132631A DE4132631A1 (de) 1991-10-01 1991-10-01 Imidazolyl-propensaeurederivate

Publications (1)

Publication Number Publication Date
ZA927501B true ZA927501B (en) 1993-05-03

Family

ID=6441873

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA927501A ZA927501B (en) 1991-10-01 1992-09-30 Imidazolyl-propenoic acid derivatives.

Country Status (15)

Country Link
US (1) US5294633A (no)
EP (1) EP0535463A1 (no)
JP (1) JPH05213938A (no)
KR (1) KR930007936A (no)
AU (1) AU646977B2 (no)
CA (1) CA2079281A1 (no)
CZ (1) CZ298892A3 (no)
DE (1) DE4132631A1 (no)
FI (1) FI924354A (no)
HU (1) HUT62577A (no)
IL (1) IL103291A0 (no)
MX (1) MX9205436A (no)
NO (1) NO923579L (no)
TW (1) TW208701B (no)
ZA (1) ZA927501B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4132633A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Cyclisch substituierte imidazolyl-propensaeurederivate
AT398202B (de) * 1991-10-04 1994-10-25 Chem Pharm Forsch Gmbh Neue imidazolderivate, verfahren zu ihrer herstellung und ihre verwendung
WO1995026188A1 (en) * 1994-03-29 1995-10-05 Merck & Co., Inc. Treatment of atherosclerosis with angiotensin ii receptor blocking imidazoles
US7879802B2 (en) 2007-06-04 2011-02-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
ES2624828T3 (es) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
EP3004138B1 (en) 2013-06-05 2024-03-13 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase c, method of making and using same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5138069A (en) * 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
EP0403158A3 (en) * 1989-06-14 1991-12-18 Smithkline Beecham Corporation Imidazolyl-alkenoic acids
ES2142789T3 (es) * 1989-06-14 2000-05-01 Smithkline Beecham Corp Acidos imidazolil-alquenoicos.
EP0479892A1 (en) * 1989-06-30 1992-04-15 E.I. Du Pont De Nemours And Company Fused-ring aryl substituted imidazoles
EP0479903B1 (en) * 1989-06-30 1996-02-21 E.I. Du Pont De Nemours And Company Substituted imidazoles useful as angiotensin ii blockers
CA2027937A1 (en) * 1989-10-25 1991-04-26 Richard M. Keenan Substituted 5-¬ (tetrazolyl)alkenyl|imidazoles
GB9017482D0 (en) * 1990-08-09 1990-09-26 Ici Plc Manufacturing process
DE4132632A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Substituierte imidazolyl-propensaeurederivate

Also Published As

Publication number Publication date
DE4132631A1 (de) 1993-04-08
AU646977B2 (en) 1994-03-10
JPH05213938A (ja) 1993-08-24
TW208701B (no) 1993-07-01
HUT62577A (en) 1993-05-28
KR930007936A (ko) 1993-05-20
CZ298892A3 (en) 1993-04-14
FI924354A (fi) 1993-04-02
FI924354A0 (fi) 1992-09-29
US5294633A (en) 1994-03-15
AU2602392A (en) 1993-04-08
CA2079281A1 (en) 1993-04-02
NO923579L (no) 1993-04-02
MX9205436A (es) 1993-04-01
HU9203124D0 (en) 1992-12-28
NO923579D0 (no) 1992-09-15
IL103291A0 (en) 1993-02-21
EP0535463A1 (de) 1993-04-07

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