ZA922504B - Novel 2-spirocyclopropyl 4-acylcephems and processes for the preparation thereof - Google Patents

Novel 2-spirocyclopropyl 4-acylcephems and processes for the preparation thereof

Info

Publication number: ZA922504B
Authority: ZA; South Africa
Prior art keywords: spirocyclopropyl; acylcephems; novel; processes; preparation
Prior art date: 1991-04-08

Application number

ZA922504A

Other languages

English (en)

Inventor

Samarendra N Maiti

David Czajowski

Charles Fiakpui

Narender A V Reddy

Paul Spevak

Ronald G Micetich

Original Assignee

Synphar Lab Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-04-08

Filing date

1992-04-07

Publication date

1993-12-07

1992-04-07 Application filed by Synphar Lab Inc filed Critical Synphar Lab Inc

1993-12-07 Publication of ZA922504B publication Critical patent/ZA922504B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Detergent Compositions (AREA)

ZA922504A 1991-04-08 1992-04-07 Novel 2-spirocyclopropyl 4-acylcephems and processes for the preparation thereof ZA922504B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/681,680 US5258377A (en)	1991-04-08	1991-04-08	2-spirocyclopropyl 4-acylcephems

Publications (1)

Publication Number	Publication Date
ZA922504B true ZA922504B (en)	1993-12-07

Family

ID=24736298

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA922504A ZA922504B (en)	1991-04-08	1992-04-07	Novel 2-spirocyclopropyl 4-acylcephems and processes for the preparation thereof

Country Status (10)

Country	Link
US (1)	US5258377A (fi)
EP (1)	EP0580650B1 (fi)
JP (1)	JPH06506207A (fi)
AT (1)	ATE169023T1 (fi)
CA (1)	CA2107892A1 (fi)
DE (1)	DE69226432D1 (fi)
FI (1)	FI934395L (fi)
HU (1)	HUT66046A (fi)
WO (1)	WO1992017482A1 (fi)
ZA (1)	ZA922504B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8811388D0 (en) *	1988-05-13	1988-06-15	Erba Carlo Spa	1,1-dioxo-cephem-4-carbothiolic acid derivatives
GB8928373D0 (en) *	1989-12-15	1990-02-21	Erba Carlo Spa	Beta-lactam derivatives
US5439904A (en) *	1993-12-07	1995-08-08	Synphar Laboratories, Inc.	2-spiro(2'-spirocycloalkyl)cyclopropyl cephalosporin sulfones as antiinflammatory and antigenerative agents
US5629306A (en)	1994-12-09	1997-05-13	Research Corporation Technologies, Inc.	7-alkylidene cephalosporanic acid derivatives and methods of using the same
US5597817A (en) *	1994-12-09	1997-01-28	Southern Methodist University	7-vinylidene cephalosporins and methods of using the same
US5760027A (en) *	1996-12-06	1998-06-02	Research Corporation Technologies, Inc.	Use of 7-alkylidene cephalosporins to inhibit elastase activity
US6407091B1 (en) *	1999-04-15	2002-06-18	Research Corporation Technologies, Inc.	β-lactamase inhibiting compounds
EP1660506A4 (en) *	2003-08-25	2009-02-25	Revaax Pharmaceuticals Llc	ORAL NEUROTHERAPEUTIC CEFAZOLINE COMPOSITIONS
CN118903385A (zh)	2017-08-24	2024-11-08	诺和诺德股份有限公司	Glp-1组合物及其用途
PE20230819A1 (es)	2020-02-18	2023-05-19	Novo Nordisk As	Composiciones y usos de glp-1

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH563396A5 (fi) *	1970-06-05	1975-06-30	Ciba Geigy Ag
US4547371A (en) *	1983-04-18	1985-10-15	Merck & Co., Inc.	Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents
EP0124081A3 (en) *	1983-05-02	1986-11-26	Merck & Co. Inc.	New substituted cephalosporin sulfones as antiinflammatory and antidegenerative agents, pharmaceutical compositions containing the same and processes for making them
US4717722A (en) *	1984-05-07	1988-01-05	Merck & Co., Inc.	Substituted 1-oxa-dethiacephalosporins as anti-inflammatory and antidegenerative agents
DE3751700D1 (de) *	1986-11-12	1996-03-21	Merck & Co Inc	Substituierte Cephalosporinsulfone als anti-entzündliche und anti-degenerative Mittel
JPH01226887A (ja) *	1988-03-07	1989-09-11	Takeda Chem Ind Ltd	３環性セファムまたはイソセファム化合物，その製造法およびエラスターゼ阻害剤
GB8808701D0 (en) *	1988-04-13	1988-05-18	Erba Carlo Spa	Beta-lactam derivatives
GB8811388D0 (en) *	1988-05-13	1988-06-15	Erba Carlo Spa	1,1-dioxo-cephem-4-carbothiolic acid derivatives
AU661453B2 (en) *	1989-10-06	1995-07-27	Synphar Laboratories, Inc.	Novel 2-spirocyclopropyl cephalosporin sulfone derivatives and processes for the preparation thereof

1991
- 1991-04-08 US US07/681,680 patent/US5258377A/en not_active Expired - Fee Related
1992
- 1992-04-07 EP EP92907957A patent/EP0580650B1/en not_active Expired - Lifetime
- 1992-04-07 ZA ZA922504A patent/ZA922504B/xx unknown
- 1992-04-07 WO PCT/CA1992/000145 patent/WO1992017482A1/en active IP Right Grant
- 1992-04-07 DE DE69226432T patent/DE69226432D1/de not_active Expired - Lifetime
- 1992-04-07 JP JP4507471A patent/JPH06506207A/ja active Pending
- 1992-04-07 AT AT92907957T patent/ATE169023T1/de not_active IP Right Cessation
- 1992-04-07 CA CA002107892A patent/CA2107892A1/en not_active Abandoned
- 1992-04-07 HU HU9302717A patent/HUT66046A/hu unknown
1993
- 1993-10-06 FI FI934395A patent/FI934395L/fi not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU1556092A (en)	1992-11-02
FI934395L (fi)	1993-10-21
WO1992017482A1 (en)	1992-10-15
HUT66046A (en)	1994-09-28
HU9302717D0 (en)	1993-12-28
ATE169023T1 (de)	1998-08-15
US5258377A (en)	1993-11-02
CA2107892A1 (en)	1992-10-09
EP0580650B1 (en)	1998-07-29
FI934395A0 (fi)	1993-10-06
EP0580650A1 (en)	1994-02-02
DE69226432D1 (de)	1998-09-03
JPH06506207A (ja)	1994-07-14
AU668503B2 (en)	1996-05-09

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