[go: up one dir, main page]

ZA91132B - Lipid-selective antioxidants and their preparation and use - Google Patents

Lipid-selective antioxidants and their preparation and use

Info

Publication number
ZA91132B
ZA91132B ZA91132A ZA91132A ZA91132B ZA 91132 B ZA91132 B ZA 91132B ZA 91132 A ZA91132 A ZA 91132A ZA 91132 A ZA91132 A ZA 91132A ZA 91132 B ZA91132 B ZA 91132B
Authority
ZA
South Africa
Prior art keywords
lipid
preparation
selective antioxidants
antioxidants
selective
Prior art date
Application number
ZA91132A
Other languages
English (en)
Inventor
Klaus-Ulrich Weithmann
Weithmann Klaus-Ulrich
Guenther Wess
Wess Guenther
Dirk Seiffge
Seiffge Dirk
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA91132B publication Critical patent/ZA91132B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/66—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/08—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • C07J41/0061—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives one of the carbon atoms being part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
ZA91132A 1990-01-09 1991-01-08 Lipid-selective antioxidants and their preparation and use ZA91132B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4000397A DE4000397A1 (de) 1990-01-09 1990-01-09 Lipidselektive antioxidantien sowie deren herstellung und verwendung

Publications (1)

Publication Number Publication Date
ZA91132B true ZA91132B (en) 1991-10-30

Family

ID=6397761

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA91132A ZA91132B (en) 1990-01-09 1991-01-08 Lipid-selective antioxidants and their preparation and use

Country Status (13)

Country Link
US (2) US5318987A (es)
EP (1) EP0436936A2 (es)
JP (1) JPH04331284A (es)
KR (1) KR910014365A (es)
AU (2) AU652928B2 (es)
CA (1) CA2033755A1 (es)
DE (1) DE4000397A1 (es)
HU (1) HU210905B (es)
IE (1) IE910059A1 (es)
NO (1) NO910075L (es)
NZ (1) NZ236709A (es)
PT (1) PT96438B (es)
ZA (1) ZA91132B (es)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU664059B2 (en) * 1991-12-20 1995-11-02 Hoechst Aktiengesellschaft Ethylenically unsaturated bile acid derivatives, processes for their preparation and precursors
EP0635011B1 (en) * 1992-04-07 1996-12-18 Merrell Pharmaceuticals Inc. Hydrazide derivatives of 3,4-dihydro-2h-1-benzopyrans
DE4312034A1 (de) * 1993-04-13 1994-10-20 Hesch Rolf Dieter Prof Dr Med Neuartige Androgene und Anabolika
DE4338316A1 (de) * 1993-11-10 1995-05-11 Jenapharm Gmbh Neue Steroide mit radikophilen Substituenten, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
ES2072223B1 (es) * 1993-11-25 1996-03-16 Lipotec Sa Liposomas encapsulando doxorubicina.
DE4439477C2 (de) * 1994-11-08 1999-10-21 Asta Medica Ag Verwendung von R,S-(+/-)-alpha-Liponsäure, R-(+)-alpha-Liponäure, S-(-)-alpha-Liponsäure in reduzierter oder oxidierter Form oder der Metabolite sowie deren Salze, Ester, Amide zur Behandlung der diabetischen Mikroangiopathie
US5951990A (en) * 1995-05-15 1999-09-14 Avon Products, Inc. Ascorbyl-phosphoryl-cholesterol
US6162450A (en) * 1995-05-15 2000-12-19 Avon Products, Inc. Uses of ascorbyl-phosphoryl-cholesterol and compositions for practicing same
CA2244535A1 (en) * 1995-05-15 2000-01-30 Avon Products, Inc. Novel uses for ascorbyl-phosphoryl-cholesterol in topical compositions
US5583239A (en) * 1995-05-30 1996-12-10 Lehigh University Antimicrobial sterol conjugates
US5607968A (en) * 1995-06-07 1997-03-04 Avon Products, Inc. Topical alkyl-2-O-L-ascorbyl-phosphates
AU740577B2 (en) * 1996-05-14 2001-11-08 Avon Products Inc. Ascorbyl-phosphoryl-cholesterol
JP3240580B2 (ja) * 1996-05-14 2001-12-17 エイボン プロダクツ インコーポレイテッド アスコルビル−ホスホリル−コレステロール
JP3588734B2 (ja) * 1996-07-26 2004-11-17 コニカミノルタホールディングス株式会社 電子写真感光体
DE19633560A1 (de) * 1996-08-21 1998-02-26 Basf Ag Chromanyl-ascorbinsäurederivate, deren Herstellung und Verwendung
AU728488B2 (en) 1997-04-02 2001-01-11 Sankyo Company Limited Dithiolan derivatives, their preparation and their therapeutic effect
JPH10298174A (ja) * 1997-04-30 1998-11-10 Showa Denko Kk アスコルビン酸誘導体及びそれを含有するビタミンｃ剤
US6127409A (en) * 1997-04-30 2000-10-03 Showa Denko Kabushiki Kaisha Ascorbic acid derivative and vitamin C preparation containing the same
US5990153A (en) * 1997-05-05 1999-11-23 Wood; John G. Ultrasonicated α-lipoic acid solutions for attenuating microvascular injury
US6090842A (en) * 1998-03-10 2000-07-18 The Regents Of The University Of California Lipoic acid analogs
WO2000010531A1 (en) 1998-08-19 2000-03-02 Rtp Pharma Inc. Injectable aqueous dispersions of propofol
DE19915576A1 (de) 1999-03-30 2000-10-05 Jenapharm Gmbh Equileninderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
IT1311922B1 (it) 1999-04-13 2002-03-20 Nicox Sa Composti farmaceutici.
WO2001000653A1 (en) * 1999-06-23 2001-01-04 Forbes Medi-Tech Inc. Conjugates of phytosterol or phytostanol with ascorbic acid and use thereof in treating or preventing cardiovascular disease
WO2001066560A2 (en) * 2000-03-07 2001-09-13 Forbes Medi-Tech Inc. Novel derivatives comprising phytosterols and/or phytostanols and alpha-lipoic and use thereof in treating or preventing cardiovascular disease, its underlying conditions and other disorders
CA2304906A1 (en) * 2000-04-07 2001-10-07 1411198 Ontario Limited 13-hode, a regulator of vascular biocompatibility and an inhibitor of cell hyperplasia
DE10028142B4 (de) * 2000-06-07 2004-03-18 Dr. Th. Böhme KG Chem. Fabrik GmbH & Co Verfahren zum Pickeln und Chromgerben
DE60125220T2 (de) * 2000-10-25 2007-04-12 Forbes Medi-Tech Inc., Vancouver Verbindungen,die ein phytosterol- und/oder ein phytostanolteil und ascorbinsäure enthalten und deren verwendung als gewichtsregulatoren
US20030232797A1 (en) * 2002-06-06 2003-12-18 Forbes Medi-Tech Inc. Novel derivatives of androstane and androstene with ascorbic acid and use thereof in treating or preventing various conditions, diseases, and disorders
AU2003243622B9 (en) * 2002-06-19 2009-07-16 Karo Bio Ab Glucocorticoid receptor ligands for the treatment of metabolic disorders
US20040133938A1 (en) * 2002-11-19 2004-07-08 Yinghui Dan Use of lipoic acid in plant culture media
US20040254357A1 (en) * 2002-12-19 2004-12-16 Zaloga Gary P. Fatty acid phenolic conjugates
CN1208052C (zh) * 2003-03-20 2005-06-29 上海家化联合股份有限公司 一种辅酶q10前体脂质体及其制备方法
JP5128799B2 (ja) * 2006-08-24 2013-01-23 株式会社アイ・ティー・オー チオクト酸誘導体を含有する生理活性組成物。
US8263653B2 (en) 2007-04-18 2012-09-11 Cornerstone Pharmaceuticals, Inc. Pharmaceutical formulations containing lipoic acid derivatives
WO2008131114A2 (en) * 2007-04-18 2008-10-30 Cornerstone Pharmaceuticals, Inc. Pharmaceutical formulations containing lipoic acid derivatives
WO2008131117A1 (en) 2007-04-18 2008-10-30 Cornerstone Pharmaceuticals, Inc. Lipoic acid derivatives
PL2220030T3 (pl) 2007-11-06 2016-07-29 Bioelectron Tech Corp Pochodne 4-(p-chinonylo)-2-hydroksybutanamidu do leczenia chorób mitochondrialnych
US7928067B2 (en) * 2009-05-14 2011-04-19 Ischemix Llc Compositions and methods for treating ischemia and ischemia-reperfusion injury
SG190794A1 (en) 2010-11-18 2013-07-31 Ischemix Llc Lipoyl compounds and their use for treating ischemic injury
DE102013226423A1 (de) 2013-12-18 2015-06-18 Henkel Ag & Co. Kgaa Haarbehandlungsmittel mit spezieller Konditioniermittelkombination
EP3188726B1 (en) 2014-06-19 2019-08-07 Rafael Pharmaceuticals, Inc. Pharmaceutical compounds
WO2015195070A1 (en) 2014-06-19 2015-12-23 Robert Shorr Pharmaceutical compounds
CN104402962B (zh) * 2014-12-16 2016-01-13 吉林农业大学 硫辛酸环戊烷并多氢菲酯c及其提取方法和药物用途
ES2952834T3 (es) 2017-04-25 2023-11-06 Ischemix Llc Lipoil-Glu-Ala para el tratamiento de daño neurodegenerativo producido por traumatismo craneoencefálico
CN110407805A (zh) * 2019-07-09 2019-11-05 江苏第二师范学院（江苏省教育科学研究院） 硫辛酸醛类衍生物及其制备方法、应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910888A (en) * 1971-08-04 1975-10-07 Medichemie A G Choleretically active esters and salts of bile acids
US4157984A (en) * 1977-06-08 1979-06-12 Z-L Limited Antioxidants, antioxidant compositions and methods of preparing and using same
DE2861037D1 (en) * 1977-12-06 1981-11-26 Battelle Memorial Institute Process and reactor for producing a treating aqueous solution containing at least hydrogenoperoxide ions and hydroxyl ions according to predetermined concentrations and use of the reactor
US4232122A (en) * 1979-01-17 1980-11-04 Z-L Limited Partnership Antioxidants, antioxidant compositions and methods of preparing and using same
US4368264A (en) * 1979-03-19 1983-01-11 Z-L Limited Partnership Fermentation methods of preparing ergostadientriols
US4234577A (en) * 1979-03-19 1980-11-18 Z-L Limited Partnership Ergostadientriols, compositions containing same, and methods of preparing and using same
IL89850A0 (en) * 1988-04-25 1989-12-15 Takeda Chemical Industries Ltd Ester of ascorbic acid 2-phosphate
DE69314626T2 (de) * 1993-06-11 1998-05-14 Agfa Gevaert Nv Neuer Typ von modifizierter Gelatine und seine Verwendung in einem DTR-Material

Also Published As

Publication number Publication date
KR910014365A (ko) 1991-08-31
HUT58757A (en) 1992-03-30
AU6189294A (en) 1994-07-21
IE910059A1 (en) 1991-07-17
AU660248B2 (en) 1995-06-15
US5318987A (en) 1994-06-07
EP0436936A2 (de) 1991-07-17
DE4000397A1 (de) 1991-07-11
PT96438B (pt) 1998-07-31
US5508275A (en) 1996-04-16
AU652928B2 (en) 1994-09-15
NO910075D0 (no) 1991-01-08
JPH04331284A (ja) 1992-11-19
NZ236709A (en) 1992-11-25
AU6921791A (en) 1991-09-05
HU210905B (en) 1995-09-28
CA2033755A1 (en) 1991-07-10
HU910028D0 (en) 1991-08-28
PT96438A (pt) 1991-10-15
NO910075L (no) 1991-07-10
EP0436936A3 (es) 1994-04-27

Similar Documents

Publication Publication Date Title
ZA91132B (en) Lipid-selective antioxidants and their preparation and use
IL116325A0 (en) Substituted 1h-imidazoles their preparation and use
ZA923516B (en) New thiopyranopyrrole derivatives and their preparation
GB9121289D0 (en) Composition and use
ZA929127B (en) Quinoline-3-carboxamides their manufacture and use
EP0482649A3 (en) Cm-chitin derivatives and use thereof
ZA929128B (en) Hydroxypyridonecarboxamides their manufacture and use
IL98088A0 (en) Tetrahydropyridazines and their use as arthropodicides
IL116014A0 (en) Iminooxymethyleneanilides their preparation and their use
ZA9110045B (en) Pyrimidinyl-and triazinyl-salicylamides and their use and preparation
GB9103631D0 (en) Composition and use
EP0442086A3 (en) Graftcopolymers, their preparation and their use
EP0456138A3 (en) Peptide-amidase and its application
NZ237380A (en) 1 hydroxyalkyl-5-nitroimidazoles and their preparation
GB9016027D0 (en) Composition and use
IL97366A (en) Aryl-propyl-amines their preparation and their use as fungicides
IL99103A0 (en) Preparation of fluorophenols,fluorohalophenols,n-acylfluoroanilines,and n-acylfluorohaloanilines
EP0459198A3 (en) Thioalkanones, procedure for their preparation and their use
IL105873A0 (en) Pyrimidinyl-and triazinyl-salicyl-and-picolyl-amides and the use and preparation thereof
ZA942246B (en) Novel imidazolo-quinoxalinones their preparation and use
IL100395A0 (en) Poly(organosilylhydrazines)and their preparation
ZA918998B (en) 3h-purines,their preparation and use
ZA925237B (en) Substituted 1-phenyl-1-benzoylamino-5-aminopentanes their preparation and use
EP0505941A3 (en) Peptifluorin and neopeptifluorin
GR900300184T1 (en) Preparation and its use