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ZA907199B - Condensed diazepinones,process for preparing them and pharmaceutical compositions containing these compounds - Google Patents

Condensed diazepinones,process for preparing them and pharmaceutical compositions containing these compounds

Info

Publication number
ZA907199B
ZA907199B ZA907199A ZA907199A ZA907199B ZA 907199 B ZA907199 B ZA 907199B ZA 907199 A ZA907199 A ZA 907199A ZA 907199 A ZA907199 A ZA 907199A ZA 907199 B ZA907199 B ZA 907199B
Authority
ZA
South Africa
Prior art keywords
preparing
compounds
pharmaceutical compositions
compositions containing
condensed diazepinones
Prior art date
Application number
ZA907199A
Inventor
Wolfhard Engel
Engel Wolfhard
Wolfgang Eberlein
Eberlein Wolfgang
Gerhard Mihm
Mihm Gerhard
Henri Doods
Doods Henri
Guenter Trummlitz
Trummlitz Guenter
Norbert Mayer
Mayer Norbert
Adriaan De Jong
De Jong Adriaan
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA907199B publication Critical patent/ZA907199B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA907199A 1989-09-11 1990-09-11 Condensed diazepinones,process for preparing them and pharmaceutical compositions containing these compounds ZA907199B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3930262A DE3930262A1 (en) 1989-09-11 1989-09-11 CONDENSED DIAZEPINONE, METHOD FOR THE PRODUCTION THEREOF AND MEDICAMENT CONTAINING THESE COMPOUNDS

Publications (1)

Publication Number Publication Date
ZA907199B true ZA907199B (en) 1992-05-27

Family

ID=6389152

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA907199A ZA907199B (en) 1989-09-11 1990-09-11 Condensed diazepinones,process for preparing them and pharmaceutical compositions containing these compounds

Country Status (17)

Country Link
EP (1) EP0417631A3 (en)
JP (1) JPH03209382A (en)
KR (1) KR910006286A (en)
AU (1) AU626452B2 (en)
CA (1) CA2025005A1 (en)
DD (1) DD299308A5 (en)
DE (1) DE3930262A1 (en)
FI (1) FI904469A0 (en)
HU (1) HU206882B (en)
IL (1) IL95622A (en)
NO (1) NO903941L (en)
NZ (1) NZ235270A (en)
PL (1) PL165197B1 (en)
PT (1) PT95259A (en)
RU (1) RU2017740C1 (en)
YU (1) YU47372B (en)
ZA (1) ZA907199B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3930266A1 (en) * 1989-09-11 1991-03-14 Thomae Gmbh Dr K CONDENSED DIAZEPINONE, METHOD FOR THE PRODUCTION THEREOF AND MEDICAMENT CONTAINING THESE COMPOUNDS
ES2355157T3 (en) 2002-07-05 2011-03-23 Targacept, Inc. N-ARILO DIAZASPIROCYCLIC COMPOUNDS AND METHODS OF PREPARATION AND USE OF THE SAME.
SE0202133D0 (en) 2002-07-08 2002-07-08 Astrazeneca Ab Novel compounds
SE0303090D0 (en) 2003-11-20 2003-11-20 Astrazeneca Ab Novel compounds
SE0303541D0 (en) 2003-12-22 2003-12-22 Astrazeneca Ab New compounds
US8809552B2 (en) * 2011-11-01 2014-08-19 Hoffmann-La Roche Inc. Azetidine compounds, compositions and methods of use
MY180688A (en) * 2012-06-13 2020-12-07 Hoffmann La Roche New diazaspirocycloalkane and azaspirocycloalkane
BR112015004111A2 (en) 2012-09-25 2017-07-04 Hoffmann La Roche new bicyclic derivatives
AR095079A1 (en) 2013-03-12 2015-09-16 Hoffmann La Roche DERIVATIVES OF OCTAHIDRO-PIRROLO [3,4-C] -PIRROL AND PIRIDINA-FENILO
WO2015078803A1 (en) 2013-11-26 2015-06-04 F. Hoffmann-La Roche Ag NEW OCTAHYDRO-CYCLOBUTA [1,2-c;3,4-c']DIPYRROL-2-YL
AU2015238537B2 (en) 2014-03-26 2019-08-01 F. Hoffmann-La Roche Ag Bicyclic compounds as autotaxin (ATX) and lysophosphatidic acid (LPA) production inhibitors
AU2015238541B2 (en) 2014-03-26 2019-09-19 F. Hoffmann-La Roche Ag Condensed [1,4]diazepine compounds as autotaxin (ATX) and lysophosphatidic acid (LPA) production inhibitors
MA41898A (en) 2015-04-10 2018-02-13 Hoffmann La Roche BICYCLIC QUINAZOLINONE DERIVATIVES
CA2992889A1 (en) 2015-09-04 2017-03-09 F. Hoffmann-La Roche Ag Phenoxymethyl derivatives
BR112018006034A2 (en) 2015-09-24 2018-10-09 Hoffmann La Roche bicyclic compounds as atx inhibitors
BR112018006024A2 (en) 2015-09-24 2020-05-12 F. Hoffmann-La Roche Ag BICYCLIC COMPOUNDS AS ATX INHIBITORS
CA2991612A1 (en) 2015-09-24 2017-03-30 F. Hoffmann-La Roche Ag New bicyclic compounds as dual atx/ca inhibitors
CR20180143A (en) 2015-09-24 2018-05-03 Hoffmann La Roche NEW BICYCLE COMPOUNDS AS DUAL INHIBITORS OF ATX / CA
JP7090099B2 (en) 2017-03-16 2022-06-23 エフ．ホフマン－ラ ロシュ アーゲー A novel bicyclic compound as an ATX inhibitor
CN110392679B (en) 2017-03-16 2023-04-07 豪夫迈·罗氏有限公司 Heterocyclic compounds useful as dual ATX/CA inhibitors
ES2951874T3 (en) * 2017-09-05 2023-10-25 Neumora Therapeutics Inc Vasopressin receptor antagonists and products and methods related thereto

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210648A (en) * 1977-05-31 1980-07-01 Boehringer Ingelheim Gmbh II-Aminoacyl-5,11-dihydro-6H-pyrido(2,3-B) (1,4)benzodiazepin-6-ones and salts thereof
DE3204153A1 (en) * 1982-02-06 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach SUBSTITUTED THIENOBENZODIAZEPINONE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING IT
DE3204403A1 (en) * 1982-02-09 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach NEW PYRIDOBENZODIAZEPINONE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
IE55898B1 (en) * 1982-09-09 1991-02-14 Warner Lambert Co Antibacterial agents
DE3726908A1 (en) * 1987-08-13 1989-02-23 Thomae Gmbh Dr K NEW CONDENSED DIAZEPINONE, PROCESS FOR THEIR MANUFACTURE AND MEDICAMENTS CONTAINING THESE COMPOUNDS
DE3930266A1 (en) * 1989-09-11 1991-03-14 Thomae Gmbh Dr K CONDENSED DIAZEPINONE, METHOD FOR THE PRODUCTION THEREOF AND MEDICAMENT CONTAINING THESE COMPOUNDS

Also Published As

Publication number Publication date
FI904469A0 (en) 1990-09-11
EP0417631A2 (en) 1991-03-20
JPH03209382A (en) 1991-09-12
RU2017740C1 (en) 1994-08-15
AU626452B2 (en) 1992-07-30
HU905852D0 (en) 1991-03-28
KR910006286A (en) 1991-04-29
NO903941L (en) 1991-03-12
AU6235290A (en) 1991-03-14
DD299308A5 (en) 1992-04-09
EP0417631A3 (en) 1991-12-11
HUT55393A (en) 1991-05-28
YU47372B (en) 1995-01-31
IL95622A (en) 1994-04-12
PL286835A1 (en) 1991-08-26
IL95622A0 (en) 1991-06-30
NO903941D0 (en) 1990-09-10
PT95259A (en) 1991-05-22
DE3930262A1 (en) 1991-03-21
HU206882B (en) 1993-01-28
CA2025005A1 (en) 1991-03-12
PL165197B1 (en) 1994-11-30
NZ235270A (en) 1991-11-26
YU171590A (en) 1993-05-28

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