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ZA903111B - 2-hydroxy-3-phenoxypropylamino compounds and pharmaceutical compositions containing them - Google Patents

2-hydroxy-3-phenoxypropylamino compounds and pharmaceutical compositions containing them

Info

Publication number
ZA903111B
ZA903111B ZA903111A ZA903111A ZA903111B ZA 903111 B ZA903111 B ZA 903111B ZA 903111 A ZA903111 A ZA 903111A ZA 903111 A ZA903111 A ZA 903111A ZA 903111 B ZA903111 B ZA 903111B
Authority
ZA
South Africa
Prior art keywords
hydroxy
compounds
phenoxypropylamino
pharmaceutical compositions
compositions containing
Prior art date
Application number
ZA903111A
Other languages
English (en)
Inventor
Ralph Howe
Howe Ralph
David James Le Count
James Le Count David
Balbir Singh Rao
Singh Rao Balbir
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Publication of ZA903111B publication Critical patent/ZA903111B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/18Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
    • C07C235/20Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18Oxygen atoms
    • C07D263/20Oxygen atoms attached in position 2
    • C07D263/24Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Saccharide Compounds (AREA)
  • Pyrane Compounds (AREA)
ZA903111A 1989-05-05 1990-04-24 2-hydroxy-3-phenoxypropylamino compounds and pharmaceutical compositions containing them ZA903111B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898910374A GB8910374D0 (en) 1989-05-05 1989-05-05 Chemical compounds

Publications (1)

Publication Number Publication Date
ZA903111B true ZA903111B (en) 1991-12-24

Family

ID=10656286

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA903111A ZA903111B (en) 1989-05-05 1990-04-24 2-hydroxy-3-phenoxypropylamino compounds and pharmaceutical compositions containing them

Country Status (25)

Country Link
EP (1) EP0426804B1 (pt)
JP (1) JPH03506037A (pt)
KR (1) KR920701123A (pt)
CN (1) CN1047857A (pt)
AT (1) ATE100439T1 (pt)
AU (1) AU622027B2 (pt)
BG (1) BG93509A (pt)
CA (1) CA2015705A1 (pt)
DD (1) DD300542A5 (pt)
DE (1) DE69006178T2 (pt)
DK (1) DK0426804T3 (pt)
ES (1) ES2062526T3 (pt)
FI (1) FI910059A0 (pt)
GB (2) GB8910374D0 (pt)
GR (1) GR1001610B (pt)
HU (1) HUT58277A (pt)
IE (1) IE63533B1 (pt)
MW (1) MW4190A1 (pt)
NO (1) NO910033L (pt)
NZ (1) NZ233425A (pt)
PL (1) PL285062A1 (pt)
PT (1) PT93954A (pt)
WO (1) WO1990013535A1 (pt)
ZA (1) ZA903111B (pt)
ZW (1) ZW6790A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9111425D0 (en) * 1991-05-28 1991-07-17 Ici Plc Chemical compounds
GB9111426D0 (en) * 1991-05-28 1991-07-17 Ici Plc Chemical compounds
US5502078A (en) * 1991-05-28 1996-03-26 Zeneca Limited Chemical compounds
NO179246C (no) * 1991-11-20 1996-09-04 Sankyo Co Aromatiske amino-alkoholderivater og mellomprodukter til fremstilling derav
GB9207964D0 (en) * 1992-04-10 1992-05-27 Ici Plc Chemical compounds
US5578638A (en) * 1993-11-05 1996-11-26 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists
US5563171A (en) * 1993-11-05 1996-10-08 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US463323A (en) * 1891-11-17 Temporary binder
GB1245148A (en) * 1968-11-18 1971-09-08 Pfizer Ltd Propanolamine derivatives
US4263323A (en) * 1976-10-07 1981-04-21 Aktiebolaget Hassle β-Receptor blocking compounds and treatment of cardiovascular disorders therewith
DE3271132D1 (en) * 1981-07-11 1986-06-19 Beecham Group Plc Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application
GB8519154D0 (en) * 1985-07-30 1985-09-04 Ici Plc Aromatic ethers

Also Published As

Publication number Publication date
DD300542A5 (de) 1992-06-17
BG93509A (bg) 1993-12-24
IE901438L (en) 1990-11-05
PL285062A1 (en) 1992-01-13
ATE100439T1 (de) 1994-02-15
GR1001610B (el) 1994-07-29
IE63533B1 (en) 1995-05-03
ZW6790A1 (en) 1991-02-27
DK0426804T3 (da) 1994-05-30
FI910059A0 (fi) 1991-01-04
EP0426804B1 (en) 1994-01-19
CA2015705A1 (en) 1990-11-05
DE69006178T2 (de) 1994-05-05
MW4190A1 (en) 1991-03-13
JPH03506037A (ja) 1991-12-26
WO1990013535A1 (en) 1990-11-15
NZ233425A (en) 1992-07-28
ES2062526T3 (es) 1994-12-16
HUT58277A (en) 1992-02-28
NO910033D0 (no) 1991-01-04
KR920701123A (ko) 1992-08-11
GB9008867D0 (en) 1990-06-20
PT93954A (pt) 1991-01-08
AU622027B2 (en) 1992-03-26
GB8910374D0 (en) 1989-06-21
NO910033L (no) 1991-03-04
HU903384D0 (en) 1991-05-28
EP0426804A1 (en) 1991-05-15
AU5540390A (en) 1990-11-29
CN1047857A (zh) 1990-12-19
GR900100332A (en) 1991-10-10
DE69006178D1 (de) 1994-03-03

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