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ZA894397B - Analgesic phenothiazine derivatives - Google Patents

Analgesic phenothiazine derivatives

Info

Publication number
ZA894397B
ZA894397B ZA894397A ZA894397A ZA894397B ZA 894397 B ZA894397 B ZA 894397B ZA 894397 A ZA894397 A ZA 894397A ZA 894397 A ZA894397 A ZA 894397A ZA 894397 B ZA894397 B ZA 894397B
Authority
ZA
South Africa
Prior art keywords
analgesic
phenothiazine derivatives
branched
linear
mixtures
Prior art date
Application number
ZA894397A
Other languages
English (en)
Inventor
Claude Garret
Garret Claude
Claude Guyon
Guyon Claude
Bernard Plau
Plau Bernard
Gerard Taurand
Taurand Gerard
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of ZA894397B publication Critical patent/ZA894397B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
    • C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
    • C07D279/28—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom with other substituents attached to the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA894397A 1988-06-10 1989-06-09 Analgesic phenothiazine derivatives ZA894397B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8807770A FR2632520B1 (fr) 1988-06-10 1988-06-10 Derives de la phenothiazine analgesiques

Publications (1)

Publication Number Publication Date
ZA894397B true ZA894397B (en) 1990-02-28

Family

ID=9367166

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA894397A ZA894397B (en) 1988-06-10 1989-06-09 Analgesic phenothiazine derivatives

Country Status (17)

Country Link
US (1) US5049669A (pt)
EP (1) EP0346238B1 (pt)
JP (1) JP2504830B2 (pt)
KR (1) KR0125575B1 (pt)
AT (1) ATE90346T1 (pt)
AU (1) AU621120B2 (pt)
CA (1) CA1325631C (pt)
DE (1) DE68906965T2 (pt)
DK (1) DK283089A (pt)
ES (1) ES2058569T3 (pt)
FR (1) FR2632520B1 (pt)
HU (1) HU205752B (pt)
IE (1) IE63300B1 (pt)
IL (1) IL90559A (pt)
MX (1) MX9203585A (pt)
PT (1) PT90813B (pt)
ZA (1) ZA894397B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2632521B1 (fr) * 1988-06-10 1990-09-14 Rhone Poulenc Sante Nouveaux derives de la phenothiazine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2632522B1 (fr) * 1988-06-10 1990-09-14 Rhone Poulenc Sante Nouveaux derives de la phenothiazine, leur preparation et les compositions qui les contiennent
FR2652084B1 (fr) * 1989-09-21 1991-10-31 Rhone Poulenc Sante Nouveaux derives de la phenothiazine, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2689013B1 (fr) * 1992-03-30 1995-05-05 Rhone Poulenc Rorer Sa Nouvelle application thérapeutique des dérivés de la phénothiazine.
FR2720940A1 (fr) * 1994-06-13 1995-12-15 Rhone Poulenc Rorer Sa Application du (+)-N-propyl [(pyrrolidinyl-1)-1 propyl-2]-10 phénothiazinecarboxamide comme antidépresseur.
PT946157E (pt) * 1996-12-16 2002-07-31 Alcon Lab Inc Utilizacao topica de agonistas kapa-opioides para o tratamento da dor ocular
US6174878B1 (en) 1999-08-31 2001-01-16 Alcon Laboratories, Inc. Topical use of kappa opioid agonists to treat otic pain
WO2006070526A1 (ja) * 2004-12-28 2006-07-06 Murata Manufacturing Co., Ltd. イオン発生ユニットおよびイオン発生装置
KR101646962B1 (ko) 2014-09-29 2016-08-10 한국과학기술연구원 CaM 저해활성을 가지는 페노싸이아진 유도체

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2956996A (en) * 1960-10-18 Alkylated phenotfflazenecarboxamede
NL222355A (pt) * 1957-11-05
US3112310A (en) * 1962-01-15 1963-11-26 Searle & Co 10-alkylaminoalkylphenothiazine-2-carboxamides
FR180F (fr) * 1964-11-30 Bruneau & Cie Lab Médicament a base de dérivés d'acide phénothiazine carboxylique-3.
FR2632521B1 (fr) * 1988-06-10 1990-09-14 Rhone Poulenc Sante Nouveaux derives de la phenothiazine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2632522B1 (fr) * 1988-06-10 1990-09-14 Rhone Poulenc Sante Nouveaux derives de la phenothiazine, leur preparation et les compositions qui les contiennent

Also Published As

Publication number Publication date
ATE90346T1 (de) 1993-06-15
CA1325631C (fr) 1993-12-28
HU205752B (en) 1992-06-29
EP0346238B1 (fr) 1993-06-09
FR2632520B1 (fr) 1990-09-14
DE68906965D1 (de) 1993-07-15
JP2504830B2 (ja) 1996-06-05
IL90559A (en) 1994-08-26
KR0125575B1 (ko) 1998-07-01
JPH037269A (ja) 1991-01-14
AU621120B2 (en) 1992-03-05
IE891865L (en) 1989-12-10
IE63300B1 (en) 1995-04-05
EP0346238A1 (fr) 1989-12-13
ES2058569T3 (es) 1994-11-01
PT90813A (pt) 1989-12-29
US5049669A (en) 1991-09-17
MX9203585A (es) 1992-09-01
HUT50464A (en) 1990-02-28
AU3624089A (en) 1989-12-21
PT90813B (pt) 1994-10-31
FR2632520A1 (fr) 1989-12-15
KR910000680A (ko) 1991-01-30
IL90559A0 (en) 1990-01-18
DK283089A (da) 1989-12-11
DK283089D0 (da) 1989-06-09
DE68906965T2 (de) 1993-12-09

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