ZA888571B - New substituted dicarboxylic acid-bis(3,5-dicarbamoyl-2,4,6-triiodoanilides),process for their production as well as x-ray contrast media containing them - Google Patents

New substituted dicarboxylic acid-bis(3,5-dicarbamoyl-2,4,6-triiodoanilides),process for their production as well as x-ray contrast media containing them

Info

Publication number: ZA888571B
Authority: ZA; South Africa
Prior art keywords: ray contrast; triiodoanilides; dicarbamoyl; dicarboxylic acid; denotes
Prior art date: 1987-11-16

Application number

ZA888571A

Other languages

English (en)

Inventor

Peter Blaszkiewicz

Blaszkiewicz Peter

Ulrich Speck

Speck Ulrich

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-11-16

Filing date

1988-11-16

Publication date

1989-08-30

1988-11-16 Application filed by Schering Ag filed Critical Schering Ag

1989-08-30 Publication of ZA888571B publication Critical patent/ZA888571B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/67—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Polyesters Or Polycarbonates (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ZA888571A 1987-11-16 1988-11-16 New substituted dicarboxylic acid-bis(3,5-dicarbamoyl-2,4,6-triiodoanilides),process for their production as well as x-ray contrast media containing them ZA888571B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19873739098 DE3739098A1 (de)	1987-11-16	1987-11-16	Neue substituierte dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6- trijod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel

Publications (1)

Publication Number	Publication Date
ZA888571B true ZA888571B (en)	1989-08-30

Family

ID=6340719

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA888571A ZA888571B (en)	1987-11-16	1988-11-16	New substituted dicarboxylic acid-bis(3,5-dicarbamoyl-2,4,6-triiodoanilides),process for their production as well as x-ray contrast media containing them

Country Status (14)

Country	Link
US (1)	US5004835A (pt)
EP (1)	EP0317492B1 (pt)
JP (1)	JP2553170B2 (pt)
KR (1)	KR970011452B1 (pt)
AT (1)	ATE106385T1 (pt)
AU (1)	AU614310B2 (pt)
DE (2)	DE3739098A1 (pt)
DK (1)	DK638088A (pt)
ES (1)	ES2053796T3 (pt)
FI (1)	FI93209C (pt)
IE (1)	IE64759B1 (pt)
NO (1)	NO175858C (pt)
PT (1)	PT89004B (pt)
ZA (1)	ZA888571B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3731542A1 (de) *	1987-09-17	1989-03-30	Schering Ag	Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
IL94718A (en) *	1989-07-05	1994-10-21	Schering Ag	Non-ionic carboxamide contrast agent and method of preparation
US5075502A (en) *	1989-12-13	1991-12-24	Mallinckrodt, Inc.	Nonionic x-ray contrast agents, compositions and methods
ES2037605B1 (es) *	1991-11-18	1994-02-01	Invest Justesa Imagen S A Cent	Metodo para preparar nuevos agentes yodados no ionicos de constraste a los rayos x.
IT1252180B (it) *	1991-12-10	1995-06-05	Bracco Ind Chimica Spa	5,5'-(1,3-propandiil) bis (imino (2-osso-2,1-etandiil)acetilimino)-bis(2,4,6-triiodo-1,3-benzendicarbossiamidi),loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono
DE69308839T2 (de) *	1992-05-15	1997-07-24	Mallinckrodt Medical Inc	Verbesserte ioversol-synthese
WO1994022810A1 (es) *	1993-04-01	1994-10-13	Centro Investigacion Justesa Imagen, S.A.	Nuevos dimeros iodados no ionicos como agentes de contraste a los rayos x, metodo para su preparacion y composiciones galenicas que los contienen
US5611342A (en) *	1994-02-15	1997-03-18	Molecular Biosystems, Inc.	Method of computer tomography imaging the gastrointestinal tract and surrounding upper abdominal tissues and organs using an orally administered low density contrast medium
WO1995026331A1 (es) *	1994-03-25	1995-10-05	Centro Investigacion Justesa Imagen, S.A.	Nuevos dimeros iodados no ionicos como agentes de contraste a los rayos x, metodo para su preparacion y composiciones farmaceuticas que los contienen
WO2012136813A2 (en)	2011-04-07	2012-10-11	Universitetet I Oslo	Agents for medical radar diagnosis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2628517C2 (de) *	1976-06-23	1985-02-21	Schering AG, 1000 Berlin und 4709 Bergkamen	Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel
IT1207226B (it) *	1979-08-09	1989-05-17	Bracco Ind Chimica Spa	Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
DE3038853A1 (de) *	1980-10-10	1982-05-27	Schering Ag, 1000 Berlin Und 4619 Bergkamen	Neue n-hydroxy-alkylierte dicarbonsaeure-bis-(3,5-dicarbamoyl-2,4,6-trijodanilide), deren herstellung und diese enthaltende roentgenkonstrastmittel (ii)
EP0108638B1 (en) *	1982-11-08	1986-07-16	NYEGAARD & CO. A/S	X-ray contrast agents
DE3731542A1 (de) *	1987-09-17	1989-03-30	Schering Ag	Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel

1987
- 1987-11-16 DE DE19873739098 patent/DE3739098A1/de not_active Ceased
1988
- 1988-11-11 DE DE3889863T patent/DE3889863D1/de not_active Expired - Lifetime
- 1988-11-11 ES ES88730249T patent/ES2053796T3/es not_active Expired - Lifetime
- 1988-11-11 EP EP88730249A patent/EP0317492B1/de not_active Expired - Lifetime
- 1988-11-11 AT AT88730249T patent/ATE106385T1/de active
- 1988-11-15 KR KR1019880014989A patent/KR970011452B1/ko not_active IP Right Cessation
- 1988-11-15 PT PT89004A patent/PT89004B/pt not_active IP Right Cessation
- 1988-11-15 DK DK638088A patent/DK638088A/da not_active Application Discontinuation
- 1988-11-15 IE IE341488A patent/IE64759B1/en not_active IP Right Cessation
- 1988-11-15 NO NO885093A patent/NO175858C/no unknown
- 1988-11-15 US US07/271,464 patent/US5004835A/en not_active Expired - Fee Related
- 1988-11-16 FI FI885295A patent/FI93209C/fi not_active IP Right Cessation
- 1988-11-16 ZA ZA888571A patent/ZA888571B/xx unknown
- 1988-11-16 JP JP63287884A patent/JP2553170B2/ja not_active Expired - Lifetime
- 1988-11-16 AU AU25169/88A patent/AU614310B2/en not_active Ceased

Also Published As

Publication number	Publication date
NO885093L (no)	1989-05-18
FI93209C (fi)	1995-03-10
DK638088D0 (da)	1988-11-15
FI885295A (fi)	1989-05-17
JPH01153667A (ja)	1989-06-15
FI885295A0 (fi)	1988-11-16
DK638088A (da)	1989-05-17
JP2553170B2 (ja)	1996-11-13
AU2516988A (en)	1989-05-18
EP0317492A3 (en)	1990-07-11
DE3889863D1 (de)	1994-07-07
NO885093D0 (no)	1988-11-15
ATE106385T1 (de)	1994-06-15
US5004835A (en)	1991-04-02
PT89004B (pt)	1993-02-26
PT89004A (pt)	1988-12-01
NO175858B (pt)	1994-09-12
NO175858C (no)	1994-12-21
EP0317492B1 (de)	1994-06-01
ES2053796T3 (es)	1994-08-01
KR890008079A (ko)	1989-07-08
AU614310B2 (en)	1991-08-29
DE3739098A1 (de)	1989-05-24
EP0317492A2 (de)	1989-05-24
FI93209B (fi)	1994-11-30
IE883414L (en)	1990-05-15
KR970011452B1 (ko)	1997-07-11
IE64759B1 (en)	1995-09-06

Publication	Publication Date	Title
AU2225188A (en)	1989-04-13	New dicarboxylic acid-bis(3,5-dicarbamoyl-2,4,6- triiodoanilides), process for their production as well as X- ray contrast media containing them
DE3167463D1 (en)	1985-01-10	N-hydroxyalkylated (3,5-dicarbamoyl)-2,4,6-triiodo anilides) of dicarboxylic acids, their production and x-ray contrast agents containing them
ES460007A1 (es)	1978-05-01	Procedimiento para la preparacion de nuevas bis (3,5-dicar- bamoil-2,4,6-triyodoanilidas) de acidos dicarboxilicos.
ZA888571B (en)	1989-08-30	New substituted dicarboxylic acid-bis(3,5-dicarbamoyl-2,4,6-triiodoanilides),process for their production as well as x-ray contrast media containing them
IL113011A (en)	1999-09-22	R-mandelic acid salt of (2s,3s)-3- (2-methoxybenzylamino)-2- phenylpiperidine
AU565492B2 (en)	1987-09-17	4-phenyl-4-oxo-buten-2-oic acids
GR3001542T3 (en)	1992-11-23	Benzofuran carboxamides with basic substituents, process for their preparation and therapeutical compositions containing them
HUT48891A (en)	1989-07-28	Process for producing substituted vinyl-cephalosporines and pharmaceutical compositions containing t them
ES2012559A6 (es)	1990-04-01	Nuevos isopolipeptidos y procedimiento para su preparacion.
SU805605A1 (ru)	1981-09-30	N-(1-адамантилметил-)-2-хлорацетамид как полупродукт дл синтеза гидрогалогенидов N-(2-оксиэтил)-аминоалкильных производных 1-адамантилметиламина
DE3378980D1 (en)	1989-02-23	Benzazepine derivatives, process for their preparation and their use as pharmaceutical compounds
IL71430A0 (en)	1984-07-31	Iminosulfonamides and process for their production,pharmaceutical compositions containing such compounds and the use thereof
NZ195220A (en)	1983-12-16	Nb-quaternary derivatives of 10-bromoajmaline or 10-bromoisoajmaline
AT383811B (de)	1987-08-25	Verfahren zur herstellung von monoalkalisalzen von 7-amino-3-cephem-4-carbonsaeurederivaten